Promoting Effect of a Mixture of 8 Herbal Extracts (SPELA 707) on Hair Growth

    January 2003
    Eun‐Young Choi, Soo-Nam Park, Seong-Uk Park, Syngjoo Choi, Byung In Ro, Myung‐Hee Chung
    TLDR SPELA 707, a mix of eight herbal extracts, may help treat hair loss by activating hair growth and increasing hair density.
    The study investigated the effects of a mixture of 8 herbal extracts, known as SPELA 707, on hair growth. The herbs included Glycyrrhizae Radix, Persicae Semen, Salviae Radix, Angelicae Gigantis Radix, Zanthoxyli Fructus, Ginseng Radix Alba, Cnidii Rhizoma, and Carthami Flos, which are traditionally used in Korean medicine for their blood circulation, wound healing, and anti-inflammatory properties. The research found that SPELA 707 significantly promoted the transition of hair from the telogen (resting) phase to the anagen (growth) phase in C3H mice. Additionally, it enhanced hair density and promoted the anagen phase in subjects with androgenetic alopecia by inhibiting steroid 5α-reductase activity, an enzyme that blocks hair growth. These findings suggested that SPELA 707 could be a potential treatment for hair loss.
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