22 citations
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June 2017 in “Advances in Clinical and Experimental Medicine” This review discusses the historical understanding and evolving diagnostic criteria for polycystic ovary syndrome without presenting new clinical findings, highlighting the multifactorial nature and associated risks of the condition.
7 citations
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January 2022 in “Case Reports in Endocrinology” This case series observed that ovarian hyperthecosis can manifest with hyperandrogenism and insulin resistance in postmenopausal women, even when serum testosterone levels are below diagnostic thresholds, suggesting potential gaps in current diagnostic criteria.
6 citations
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August 2023 in “European journal of endocrinology” This review discusses the 2023 International Guideline for PCOS assessment and management, highlighting updated evidence-based recommendations and practice points aimed at improving care and health outcomes, but notes that research quality remains generally low to moderate.
2 citations
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May 2023 in “Current Nutrition Reports” This review summarizes various nutritional approaches and supplements, such as the Mediterranean and ketogenic diets and probiotics, as potential strategies to improve polycystic ovary syndrome symptoms, reporting no new clinical results.
1 citations
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May 2020 in “Reproductive Endocrinology” This review discusses the pathogenesis and diagnosis of alopecia and acne, emphasizing the need for coordinated treatment approaches in conditions like FPHL/AGA and complex acne, but reports no new clinical results.
October 2025 in “Journal of the Endocrine Society” In this case report, a 21-year-old female with familial partial lipodystrophy type 2 and hyperandrogenism was found to have a rare Sertoli cell tumor of the ovary, highlighting an unusual presentation where links between these two rare conditions are still unknown.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case study highlights a testosterone- and cortisol-secreting adrenal oncocytic neoplasm in an 18-year-old woman, illustrating the role of surgical excision in resolving hyperandrogenism and restoring menstruation.
March 2025 in “JAAD reviews.” This study suggests bicalutamide may be effective in reducing hair loss severity in female pattern hair loss, particularly when other antiandrogen therapies are less effective due to hyperandrogenic conditions.
January 2025 in “Journal of Clinical Medicine” This study found that among Portuguese women with hirsutism, polycystic ovary syndrome was the most prevalent cause, associated with distinct hormonal features and higher BMI compared to controls.
October 2024 in “Journal of the Endocrine Society” This case report describes a patient with an ovarian steroid cell tumor that initially presented as non-classical adrenal hyperplasia, emphasizing the difficulty in differential diagnosis with hyperandrogenism and the importance of close clinical monitoring.
October 2024 in “Journal of the Endocrine Society” This case report highlights the challenge of differentiating between non-classical adrenal hyperplasia and steroid cell tumors of the ovary in a patient presenting with hyperandrogenism.
April 2024 in “Russian Journal of Preventive Medicine” This review discusses how skin changes like acanthosis nigricans and psoriasis can indicate metabolic syndrome components such as insulin resistance and dyslipidemia, suggesting a potential role for early diagnosis and treatment in reducing cardiovascular risks associated with the syndrome.
February 2024 in “Clinical and Experimental Obstetrics & Gynecology” This study found no significant differences in fat distribution between Thai women with and without polycystic ovary syndrome, though PCOS women with abnormal glucose tolerance showed higher arm fat.
December 2022 in “Cureus” This study found that clinical and biochemical markers of hyperandrogenism were more common in post-adolescent and early adult-onset acne among women than in adolescent acne.
August 2022 in “RECISATEC” This article discusses androgenetic alopecia, its progression, signs of hyperandrogenism, and impacts on quality of life, without presenting new clinical findings.
January 2022 in “Journal of Morphological Sciences” This case report presents a 60-year-old woman with virilization and elevated adrenal androgens, where a bilateral salpingo-oophorectomy confirmed ovarian steroid cell tumor NOS, and her symptoms resolved post-operatively.
May 2021 in “Journal of the Endocrine Society” This case report describes the rare association of an ovarian Leydig cell tumor and primary hyperparathyroidism in a postmenopausal woman, highlighting the importance of considering rare causes in patients with virilizing symptoms.
April 2021 in “International Journal of Research in Dermatology” This study found that hormonal abnormalities are not very common in adult females with acne, although some patients showed indicators of hyperandrogenism.
January 2021 in “ISGE series” This article discusses PCOS, highlighting its association with insulin resistance and chronic inflammation, and suggests that nutrition, exercise, and supplements may improve body composition and metabolic function, but reports no new clinical results.
May 2020 in “Scientific periodicals of Ukraine” This review discusses the pathogenesis and treatment approaches for non-scarring alopecia and acne, highlighting the role of genetic factors, androgens, and metabolic risks but reports no new clinical results.
April 2019 in “Journal of the Endocrine Society” This case report described a 62-year-old postmenopausal woman with hirsutism whose symptoms improved after a hysterectomy and bilateral oophorectomy, revealing bilateral ovarian hyperthecosis.
January 2020 in “International Journal of Trichology” This case study reported two instances of female androgenetic alopecia with male pattern reversed after surgical removal of an ovarian tumor.
August 2023 in “Journal of Cosmetic Dermatology” This study observed that in a mouse model of androgenetic alopecia, treatments with LTF, 5% minoxidil, and LTF-DPC-EXO significantly promoted hair regeneration compared to the model group, potentially through modulation of the PI3K/AKT signaling pathway.
53 citations
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November 2021 in “Molecular Human Reproduction” This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.
26 citations
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December 2020 in “International Journal of Molecular Sciences” This review explores current and emerging treatments for polycystic ovary syndrome, focusing on managing hyperandrogenism and cardiometabolic risk, but reports no new clinical results.
25 citations
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April 1988 in “Geburtshilfe und Frauenheilkunde” In this study, treatment targeting the estrogen-androgen balance reduced hair loss in 74 out of 104 women with androgenetic alopecia, with some experiencing hair regrowth.
2 citations
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November 2022 in “Bioscience Reports” This review explores the similarities between polycystic ovary syndrome and hemochromatosis in terms of iron overload and suggests that addressing gut dysbiosis might help manage iron levels in these conditions.
1 citations
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January 2023 in “Metabolites” This review discusses the relationship between gut microbiota and polycystic ovarian syndrome (PCOS), including its potential mechanisms and the role of alterations in microbiome composition on PCOS pathophysiology.
January 2023 in “WikiJournal of Medicine” This review discusses alternative androgen pathways, including the "backdoor" pathway and pathways to 11-oxygenated steroids, and reports no new clinical results; the authors aim to clarify these concepts for better patient treatment.
This study reported that women with acanthosis nigricans and insulin resistance often exhibit signs of hyperandrogenism, including hirsutism, and have elevated fasting plasma insulin compared to controls.