Clinical and Epidemiological Characteristics and Hormonal Profile of Adult Females with Acne Vulgaris: A Cross-Sectional Study from a Tertiary Care Hospital

April 2021 in “ International Journal of Research in Dermatology ”

Nidhi Shah, Faaria Ali, Aswathy Radhakrishnan, Parag Chaudhari, Anant Patil, Sharmila Patil

acne vulgaris hirsutism menstrual irregularity testosterone luteinizing hormone follicle-stimulating hormone insulin hyperandrogenism acne LH FSH

TLDR Most adult females with acne do not have hormonal imbalances, but some show signs of excess male hormones.

This cross-sectional study from 2021 examined the clinical and epidemiological characteristics and hormonal profile of 51 adult females with acne, aged over 25 years. The study found that 70.59% of patients had persistent acne, with 78.43% having grade 2 acne. Oily skin was observed in 52.94% of patients, while hirsutism and menstrual irregularity were present in 47.06% and 25.49% of patients respectively. Pigmentation and scarring were seen in 52.94% and 68.63% of patients respectively. Elevated testosterone levels were found in 15.69% of patients, while 9.80% had elevated luteinizing hormone (LH) levels and decreased follicle-stimulating hormone (FSH) levels. Raised insulin levels were seen in 15.69% of patients. The study concluded that hormonal imbalances are not very common in adult female patients with acne, but some patients do show laboratory markers of hyperandrogenism.

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