Efficacy and Safety of Tracnil Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study

    Ezhil Arasan Ramanan, Sailatha Ravi, K R Radha Anbu, Margaret Michael
    Studysummary In this study, 33 overweight women with normal hormone levels but showing PCOS symptoms experienced substantial reductions in acne lesions and improvements in hirsutism and menstrual irregularities after 8 weeks of Tracnil™ treatment, with minimal adverse reactions reported.
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    Research cited in this study 12

    1. Hormonal Treatment of Acne Vulgaris: An Update Clinical, Cosmetic and Investigational Dermatology · 2016
    2. Correlation of Skin Changes With Hormonal Changes in Polycystic Ovarian Syndrome: A Cross-Sectional Clinical Study Indian Journal of Dermatology · 2015
    3. Polycystic Ovary Syndrome: A Review for Dermatologists Journal of The American Academy of Dermatology · 2014
    4. Acne as a Chronic Systemic Disease Clinics in Dermatology · 2013
    5. The Role of Androgen and Androgen Receptor in Skin-Related Disorders Archives of Dermatological Research · 2012
    6. The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report Fertility and Sterility · 2008
    7. Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred Because of Clinical Hyperandrogenism The Journal of Clinical Endocrinology and Metabolism · 2006
    8. Current Recommendations for the Diagnostic Evaluation and Follow-Up of Patients Presenting with Symptomatic Polycystic Ovary Syndrome Best Practice & Research in Clinical Obstetrics & Gynaecology · 2004
    9. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome Fertility and Sterility · 2004
    10. Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2002
    11. Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2002
    12. Acne American journal of clinical dermatology · 2002

    Related research 3

    1. The Effect of Alfacalcidiol and Metformin on Phenotype Manifestations in Women with Polycystic Ovary Syndrome – A Preliminary Study Physiological Research · 2016
    2. Effect of Metformin Therapy in Females Visiting Dermatologist for Acne Vulgaris Having Endocrine and Sonographic Characteristics of Polycystic Ovary Syndrome (PCOS) 2013
    3. Diagnosis and Management of the Dermatologic Manifestations of Polycystic Ovary Syndrome Dermatologic therapy · 2006