Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing

    September 2002 in “ ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation ”
    Gillian S. Ashcroft, Stuart J. Mills
    Studysummary This study found that reducing testosterone levels in male mice accelerates wound healing and decreases inflammation, suggesting a potential therapeutic target for improving wound repair in elderly males.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jci.org →
    Discuss this study in the Community →

    Research cited in this study 4

    1. Impaired Wound Healing in Transgenic Mice Overexpressing the Activin Antagonist Follistatin in the Epidermis EMBO journal · 2001
    2. 17β-Estradiol and ICI-182780 Regulate the Hair Follicle Cycle in Mice Through an Estrogen Receptor-α Pathway Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism · 2000
    3. Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair EMBO journal · 1999
    4. The Role of the Hairless (Hr) Gene in the Regulation of Hair Follicle Catagen Transformation American Journal Of Pathology · 1999