Polycystic Ovary Syndrome and Iron Overload: Biochemical Link and Underlying Mechanisms with Potential Novel Therapeutic Avenues

    November 2022 in “ Bioscience Reports ”
    Marilyn Mathew, Sathish Sivaprakasam, J.L. Phy … Vadivel Ganapathy
    Studysummary This review explores the similarities between polycystic ovary syndrome and hemochromatosis in terms of iron overload and suggests that addressing gut dysbiosis might help manage iron levels in these conditions.
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    Research cited in this study 8

    1. Effect of Phlebotomy Versus Oral Contraceptives Containing Cyproterone Acetate on Clinical and Biochemical Parameters in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial Journal of Ovarian Research · 2019
    2. Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee The Journal of Clinical Endocrinology and Metabolism · 2019
    3. Endocrinology of Hirsutism: From Androgens to Androgen Excess Disorders Frontiers of Hormone Research · 2019
    4. Polycystic Ovary Syndrome: Comprehensive Overview Obstetrics & Gynecology · 2018
    5. Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update Reproductive Biology and Endocrinology · 2016
    6. Low Starch/Low Dairy Diet Results in Successful Treatment of Obesity and Co-Morbidities Linked to Polycystic Ovary Syndrome Journal of obesity and weight loss therapy · 2015
    7. Effect of a Low-Starch/Low-Dairy Diet on Fat Oxidation in Overweight and Obese Women with Polycystic Ovary Syndrome Applied Physiology, Nutrition, and Metabolism · 2014
    8. Pharmacotherapy of Polycystic Ovary Syndrome: An Update Fundamental & Clinical Pharmacology · 2011

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    1. Polycystic Ovary Syndrome and Iron Overload: Biochemical Link and Underlying Mechanisms with Potential Novel Therapeutic Avenues Bioscience Reports · 2022