Diagnostic Challenges in Ovarian Hyperthecosis: Clinical Presentation with Subdiagnostic Testosterone Levels

    January 2022 in “ Case Reports in Endocrinology ”
    S. Shah, Callie Torres, Naser Eddin Gharaibeh
    Studysummary This case series observed that ovarian hyperthecosis can manifest with hyperandrogenism and insulin resistance in postmenopausal women, even when serum testosterone levels are below diagnostic thresholds, suggesting potential gaps in current diagnostic criteria.
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    Research cited in this study 3

    1. Clinical Case Seminar: Postmenopausal Androgen Excess - Challenges in Diagnostic Work-Up and Management of Ovarian Thecosis Clinical Endocrinology · 2017
    2. New Onset Alopecia and Hirsutism in a Postmenopausal Woman Gynecological Endocrinology · 2009
    3. A Prospective Study of the Prevalence of Clear-Cut Endocrine Disorders and Polycystic Ovaries in 350 Patients Presenting with Hirsutism or Androgenic Alopecia Clinical Endocrinology · 1994

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    3. Diagnosis of Hyperandrogenism: Clinical Criteria Best Practice & Research Clinical Endocrinology & Metabolism · 2006