Female Androgenetic Alopecia with Male Pattern Caused by an Androgen-Producing Tumor

January 2020 in “ International Journal of Trichology ”

Angelica Ruiz Dueñas, Luis Alberto Florentín Dueñas, Valeria Dayana Gómez Sánchez, Ivonne Deyanira García Rico

female androgenetic alopecia male pattern baldness androgen-producing tumor ovarian tumor Leydig cell tumor stromal luteoma hyperandrogenism testosterone alopecia hirsutism seborrhea FAGA-M male pattern hair loss hair loss high testosterone hair thinning excessive hair growth oily skin

TLDR Androgen-producing ovarian tumors can cause male-pattern hair loss in women.

The document described two cases of female androgenetic alopecia with male pattern (FAGA-M) caused by androgen-producing ovarian tumors. In the first case, a 62-year-old woman exhibited alopecia, hirsutism, and seborrhea, with elevated testosterone levels, leading to the discovery of a right ovarian Leydig cell tumor. Surgical removal resulted in significant improvement. The second case involved a 73-year-old woman with similar symptoms and an ovarian stromal luteoma, which was also surgically removed, resulting in partial improvement. The study highlighted the importance of considering hyperandrogenism and potential androgen-secreting tumors in postmenopausal women presenting with FAGA-M.

View this study on ijtrichology.com →

Discuss this study in the Community →

Research cited in this study

6 / 6 results

research Polycystic Ovary Syndrome in Adult Women

13 citations, March 2019 in “Medicina Clínica (english Edition)”

PCOS is a common hormonal disorder in women that can affect skin, fertility, and metabolism, and treatment is tailored to individual needs.

research Female Pattern Hair Loss: A Clinical and Pathophysiological Review

91 citations, August 2015 in “Anais Brasileiros De Dermatologia”

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

research Evidence-Based Approach to Cutaneous Hyperandrogenism in Women

42 citations, July 2015 in “Journal of The American Academy of Dermatology”

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

research The Female Pattern Hair Loss: Review of Etiopathogenesis and Diagnosis

35 citations, January 2014 in “BioMed Research International”

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

research Female Pattern Hair Loss: Causes, Diagnosis, and Treatment Options

23 citations, January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

research Role of Genetics and Sex Steroid Hormones in Male Androgenetic Alopecia and Female Pattern Hair Loss: An Update

87 citations, March 2011 in “Australasian Journal of Dermatology”

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Related Community Posts Join

6 / 1000+ results

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community First patient dosed with Pyrilutamide (Kintor) Phase III

in Research/Science 202 upvotes 2 years ago

First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 160 upvotes 1 year ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community 1 year on fin. No results. I give up.

in Finasteride/Dutasteride 43 upvotes 2 years ago

A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.

community The story of RU58841/ PSK3841

in Research 622 upvotes 4 months ago

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

Related Research

8 / 8 results

The Diagnosis of Androgenetic Alopecia in Children: Considerations of Pathophysiological Plausibility

research Hair and Scalp Diseases

12 citations, February 2008 in “CRC Press eBooks”

The document explains different hair and scalp conditions and their treatments.

research Female Pattern Hair Loss, Sebum Excretion, and the End-Organ Response to Androgens

31 citations, October 2005 in “British Journal of Dermatology”

Hair loss in women not always linked to increased oil production; other factors may be involved.

research Hyperandrogenism and Pilosebaceous Follicles

November 1993 in “PubMed”

High levels of androgens can cause skin issues like acne, hair loss, and excessive hair growth.