The Relationship Between Acne and Other Hyperandrogenism Signs

    September 2016 in “ Journal of skin and stem cell
    Leila Khezrian, Ameneh Yazdanfar, Zahra Azizian, Parvaneh Hassani, Mahtab Feyzian
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    TLDR Acne is strongly linked to high BMI, hair loss, menstrual issues, family history, and eating too many sweets and fatty foods, but not to excessive hair growth.
    A case-control study conducted 7 years ago at Farshchian hospital in Hamadan, Iran, involving 110 female patients with acne and 110 control subjects, found a strong association between acne, higher Body Mass Index (BMI), alopecia, menstrual dysfunction, positive familial history, and overconsumption of sweet and fatty foods. No link was found between acne and hirsutism. The study also noted that most patients experienced a worsening of acne just before menstruation and that the peak incidence of alopecia in the acne group was at stage 2, indicating progression to an adult hairline. Despite normal serum androgen levels, hormonal therapies were found to be effective in women with premenstrual acne flare-ups. The study concluded that hyperandrogenism should be evaluated in girls with premature pubarche, unusual acne, androgenetic alopecia, and obesity.
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