Clinical Markers of Androgenicity in Acne Vulgaris

    December 1988 in “ British Journal of Dermatology ”
    R. A. Sheehan-Dare, B.R. Hughes, W. J. Cunliffe
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    TLDR Acne severity in women may not be linked to increased male hormone indicators like excess body hair, menstrual irregularities, or hair loss.
    In a 1988 study with 268 female participants aged 12-44, researchers found no significant correlation between acne severity and clinical markers of androgenicity, including hirsutism, menstrual irregularity, and androgenic alopecia. The study concluded that hyperandrogenemia might not be a necessary factor for the development of acne vulgaris in women, suggesting that other factors could be responsible for the condition. Despite potential biases such as non-participation and observer awareness, the findings indicated that most women with acne did not exhibit abnormalities in other androgen target organs.
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