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    Glossary Oxidative Stress

    imbalance between free radicals and antioxidants causing cellular damage

    Oxidative stress refers to an imbalance between free radicals (unstable molecules that can damage cells) and antioxidants (molecules that neutralize free radicals) in the body. This imbalance can lead to cellular damage, also known as oxidative damage or oxidative injury, and is implicated in various conditions, including aging, cancer, and hair loss disorders like alopecia.

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    Research 30 of 1000+

    1. 705 Particulate matter induces inflammatory response in human outer root sheath cells via oxidative stress-dependent MAPK and JAK-STAT signaling pathways 2022
    2. Genome-wide p63-Target Gene Analyses Reveal TAp63/NRF2-Dependent Oxidative Stress Responses Cancer Research Communications · 2024 · 7 citations
    3. Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress during Hair Cycling PloS one · 2015 · 22 citations
    4. Evaluation of Personalized Skincare Through in-silico Gene Interactive Networks and Cellular Responses to UVR and Oxidative Stress Clinical Cosmetic and Investigational Dermatology · 2022 · 11 citations
    5. Deletion of vitamin D receptor with calcium sensing receptor in keratinocytes promotes epidermal tumorigenesis by limiting dna repair and oxidative stress response genes The Journal of Steroid Biochemistry and Molecular Biology · 2026
    6. Modulating the Antioxidant Response for Better Oxidative Stress-Inducing Therapies: How to Take Advantage of Two Sides of the Same Medal? Biomedicines · 2022 · 29 citations
    7. miR‐200a‐3p in Human Umbilical Cord Mesenchymal Stem Cell‐Derived Exosomes Attenuates UVB‐Induced Skin Inflammatory Response and Oxidative Stress via Keap1‐Nrf2 Pathway Stem Cells International · 2025
    8. The Interplay between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation Biomedicines · 2022
    9. Adult skin acute stress responses to short‐term environmental and internal aggression from exposome factors Journal of the European Academy of Dermatology and Venereology · 2021 · 37 citations
    10. Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion 2011 · 30 citations
    11. Trichotillomania: a good response to treatment with N-acetylcysteine Anais Brasileiros de Dermatologia · 2017 · 27 citations
    12. Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions Cell Proliferation · 2021 · 7 citations
    13. Effective amelioration of hepatic inflammation and insulin response in high fat diet-fed rats via regulating AKT/mTOR signaling: Role of Lepidium sativum seed extracts Journal of ethnopharmacology · 2020 · 14 citations
    14. Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells Molecular Medicine Reports · 2015 · 12 citations
    15. Reply to letter to the editor: “A response to ‘Male balding is a major risk factor for severe COVID-19’” Journal of The American Academy of Dermatology · 2020 · 1 citations
    16. The effect of antioxidants administration on the response rate in patients with alopecia areata ˜Al-œMağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ · 2008
    17. Understanding the biochemical properties of human hair keratins : self-assembly potential and cell response 2020
    18. In situ formed fluorescent gold nanoclusters inhibit hair follicle regeneration in oxidative stress microenvironment via suppressing NFκB signal pathway Chinese Chemical Letters · 2024
    19. LB1017 A novel link between human hair follicle neuroimmunology and mitochondrial biology: Substance P increases intrafollicular oxidative stress and mitochondrial biogenesis Journal of Investigative Dermatology · 2022
    20. Graphene oxide and indole-3-acetic acid cotreatment regulates the root growth of Brassica napus L. via multiple phytohormone pathways BMC plant biology · 2020 · 34 citations
    21. Epidermolysis Bullosa Simplex Keratinocytes Show Disturbed Mitochondrial Positioning and Activity 2020 · 3 citations
    22. Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts Oncotarget · 2017 · 32 citations
    23. 519 The role of the leaky gut in the development of alopecia areata 2019
    24. Formation of the cornified envelope Experimental dermatology · 2005 · 3 citations
    25. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2022
    26. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2021
    27. Environmental Air Pollutants Affecting Skin Functions with Systemic Implications International Journal of Molecular Sciences · 2023 · 70 citations
    28. Pathophysiology of the Behçet's Disease Pathology Research International · 2011 · 34 citations
    29. Multimodal roles of transient receptor potential channel activation in inducing pathological tissue scarification Frontiers in Immunology · 2023 · 7 citations
    30. Cellular senescence and polycystic ovary syndrome: mechanisms and therapeutic strategies from a new perspective Annals of Medicine · 2025 · 2 citations