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PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

TNFα helps grow and maintain liver cells in 3D culture for a long time.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Activating Notch signaling can kill basal cell carcinoma cells.

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

PRP helps skin heal, possibly through special cells called telocytes.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Engineered vesicles from macrophages help hair growth in mice and humans.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Plant extracts may help prevent or reverse hair graying.

The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

Old hair follicles grew better when moved to a young environment.

SOX9 is essential for the development of various organs and hair follicles.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

Researchers created a long-lasting mouse skin cell strain that may help with hair growth research and treatments.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.

Stem cell therapy shows promise for hair loss treatment, but more research is needed to confirm its effectiveness.

Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.

Stem-cell therapy shows promise for skin conditions but needs more research.

New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Skin organoids help improve wound healing and tissue repair.