Stem-Cell Therapy in Dermatology: Challenges and Opportunities

The document discusses the potential and challenges of stem-cell therapy in dermatology, highlighting its promise in treating conditions like atopic dermatitis, chronic urticaria, pemphigus, epidermolysis bullosa, psoriasis, vitiligo, systemic sclerosis, morphea, systemic lupus erythematosus, skin rejuvenation, androgenetic alopecia, and wound healing. Mesenchymal stem cells (MSCs) and hematopoietic stem-cell transplantation (HSCT) have shown significant clinical improvements in various studies, though issues like cell heterogeneity, dosage optimization, safety concerns, and regulatory hurdles remain. The need for larger clinical trials and further research to confirm long-term efficacy and safety is emphasized.