Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair

    October 2022 in “ Annual review of cell and developmental biology ”
    Emily Scott-Solomon, Ya‐Chieh Hsu
    Studysummary This review discusses the roles of peripheral nerves in stem cell and immune responses within the skin and hematopoietic system, emphasizing their potential in developing new therapies; it reports no new experimental results.
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    Research cited in this study 12

    1. Building and Maintaining the Skin Cold Spring Harbor Perspectives in Biology · 2021
    2. Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence Nature · 2021
    3. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells Cell · 2020
    4. Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells Nature · 2020
    5. The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development eLife · 2019
    6. External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway Proceedings of the National Academy of Sciences of the United States of America · 2018
    7. Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer Wiley Interdisciplinary Reviews-Developmental Biology · 2017
    8. The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons Cell · 2011
    9. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    10. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011
    11. The Basement Membrane Of Hair Follicle Stem Cells Is A Muscle Cell Niche Cell · 2011
    12. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005