Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis

    February 2019 in “ Stem cells international ”
    R. G. Vasyliev, Olga Gubar, Inna Gordiienko, L. S. Litvinova, A. E. Rodnichenko, В. В. Шуплецова, Alona Zlatska, K. А. Yurova, Н. М. Тодосенко, Veronika E. Khadzhynova, Mariia V. Shulha, С. Н. Новикова, Dmytro Zubov
    TLDR Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
    The study compared neural crest-derived stem cells (NCSCs) from human hair follicles (HF) and skin dermis (SD) to evaluate their potential for regenerative medicine. Both HF and SD NCSCs expressed key neural crest markers and demonstrated similar differentiation abilities. However, SD NCSCs exhibited a higher growth rate, more homogeneous marker expression, and produced higher levels of growth factors and cytokines, making them more suitable for large-scale expansion and therapeutic applications. The study involved 5 healthy male donors aged 20 to 28 years and concluded that SD NCSCs might be more efficient for clinical use due to their superior growth characteristics.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 62 results

      community I enjoy taking finasteride every day

      in Finasteride/Dutasteride  241 upvotes 6 months ago
      Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 2 years ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community Balding, short, small penis. What is the point of living…

      in Treatment  405 upvotes 3 years ago
      A 24 year old male struggling with the physical and mental effects of balding, being short, and having a micropenis. Suggested treatments include taking medications such as finasteride and minoxidil, lifting weights, and trying not to compare himself to others.

    Similar Research

    5 / 1000+ results