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GlossaryNeural Crest Stem Cells (NCSCs)

originate from the neural crest and can become various cell types

Neural Crest Stem Cells (NCSCs) are a type of multipotent stem cell that originate from the neural crest, a transient structure in vertebrate embryos. These cells have the remarkable ability to differentiate into a diverse range of cell types, including neurons, glial cells, melanocytes, and even some types of connective tissue. This versatility makes them crucial for the development of various tissues and organs, and they are a significant focus in regenerative medicine and developmental biology research.

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research Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis

11 citations, February 2019 in “Stem cells international”

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

research Rapid Preparation of a Noncultured Skin Cell Suspension That Promotes Wound Healing

5 citations, March 2017 in “Cell and Tissue Banking”

Researchers developed a new method to quickly prepare skin cells that improve wound healing in rats.

research Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells

3 citations, August 2014 in “Cellular reprogramming”

Hair follicle stem cells need all reprogramming factors to become pluripotent.

Human Hair Follicle Regeneration With Trichogenic Human Dermal Papilla Precursor Cells Derived From Induced Pluripotent Stem Cells

research Human Hair Follicle Regeneration With Trichogenic Human Dermal Papilla Precursor Cells Derived From Induced Pluripotent Stem Cells

April 2017 in “Journal of Investigative Dermatology”

Stem cells can create hair follicles, potentially treating permanent hair loss, and healthy skin and hair depend on mitochondrial function and special fats.

research Human Epidermal Neural Crest Stem Cells as a Source of Schwann Cells

44 citations, January 2015 in “Development”

Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.

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