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GlossaryNeural Crest Stem Cells (NCSCs)

originate from the neural crest and can become various cell types

Neural Crest Stem Cells (NCSCs) are a type of multipotent stem cell that originate from the neural crest, a transient structure in vertebrate embryos. These cells have the remarkable ability to differentiate into a diverse range of cell types, including neurons, glial cells, melanocytes, and even some types of connective tissue. This versatility makes them crucial for the development of various tissues and organs, and they are a significant focus in regenerative medicine and developmental biology research.

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research EGF–FGF2 Stimulates the Proliferation and Improves the Neuronal Commitment of Mouse Epidermal Neural Crest Stem Cells (EPI-NCSCs)

29 citations , June 2014 in “Experimental Cell Research”

EGF–FGF2 helps mouse stem cells grow and become more like nerve cells.

research Prenatal Transplantation of Epidermal Neural Crest Stem Cells in Malformation of Cortical Development Mouse Model

5 citations , December 2016 in “Microscopy Research and Technique”

EPI-NCSCs from hair follicles may help treat brain development issues in mice.

research Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis

11 citations , February 2019 in “Stem cells international”

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

Rapid Preparation of a Noncultured Skin Cell Suspension That Promotes Wound Healing

research Rapid Preparation of a Noncultured Skin Cell Suspension That Promotes Wound Healing

5 citations , March 2017 in “Cell and Tissue Banking”

Researchers developed a new method to quickly prepare skin cells that improve wound healing in rats.

research The Suppression Effects of Fat Mass and Obesity Associated Gene on Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocytes by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor

4 citations , February 2023 in “International Journal of Stem Cells”

The FTO gene hinders stem cells in hair follicles from becoming pigment cells.

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