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GlossaryHematopoietic Stem Cells (HSCs)

produce all types of blood cells in bone marrow

Hematopoietic Stem Cells (HSCs) are a type of stem cell found in the bone marrow that are responsible for producing all the different types of blood cells, including red blood cells, white blood cells, and platelets. These cells have the unique ability to both self-renew, creating more HSCs, and differentiate into various specialized blood cells, making them crucial for maintaining a healthy and functional blood system.

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research Runx Family Genes in Tissue Stem Cell Dynamics

6 citations , January 2017 in “Advances in Experimental Medicine and Biology”

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

research A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis

254 citations , January 2012 in “Nature Reviews Molecular Cell Biology”

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Protein Kinase C Epsilon, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells

research Protein Kinase C Epsilon, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells

10 citations , January 2013 in “Journal of skin cancer”

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

research Stem Cells in Tissue Engineering

3 citations , January 2014 in “Elsevier eBooks”

Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.

Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair-Follicle-Derived Stem Cells to Differentiate into Neurons and Glia

research Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair-Follicle-Derived Stem Cells to Differentiate into Neurons and Glia

6 citations , September 2020 in “Advanced Biology”

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

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