Evo Devo of the Vertebrate Integument

    June 2023 in “ Journal of developmental biology ”
    Danielle Dhouailly
    Studysummary In this study, researchers propose that different vertebrate skin appendages, such as hair, feathers, and scales, evolved in parallel from a shared ancestral cell structure associated with teeth, dating back approximately 420 million years ago.
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    Research cited in this study 24

    1. The Developmental Basis of Fingerprint Pattern Formation and Variation Cell · 2023
    2. Teeth outside the mouth: The evolution and development of shark denticles Evolution & Development · 2023
    3. A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells Stem Cell Research & Therapy · 2021
    4. Feather Arrays Are Patterned by Interacting Signaling and Cell Density Waves PLoS Biology · 2019
    5. Comprehensive Molecular and Cellular Studies Suggest Avian Scutate Scales Are Secondarily Derived from Feathers, and More Distant from Reptilian Scales Scientific Reports · 2018
    6. Hierarchical Patterning Modes Orchestrate Hair Follicle Morphogenesis PLoS Biology · 2017
    7. The Process of Cornification Evolved From the Initial Keratinization in the Epidermis and Epidermal Derivatives of Vertebrates: A New Synthesis and the Case of Sauropsids International review of cell and molecular biology · 2016
    8. Early Inductive Events in Ectodermal Appendage Morphogenesis Seminars in cell & developmental biology · 2014
    9. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    10. Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation Development · 2012
    11. Reptile Scale Paradigm: Evo-Devo, Pattern Formation and Regeneration The International Journal of Developmental Biology · 2009
    12. Genetic Interplays Between Msx2 And Foxn1 Are Required For Notch1 Expression And Hair Shaft Differentiation Developmental Biology · 2008
    13. Identification of Reptilian Genes Encoding Hair Keratin-Like Proteins Suggests a New Scenario for the Evolutionary Origin of Hair Proceedings of the National Academy of Sciences · 2008
    14. Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface ˜The œAmerican journal of pathology · 2008
    15. Dlx3 Is a Crucial Regulator of Hair Follicle Differentiation and Cycling Development · 2008
    16. BMP2 And BMP7 Play Antagonistic Roles In Feather Induction Development · 2008
    17. Phylogeny of the Hair Follicle: The Sebogenic Hypothesis Journal of Investigative Dermatology · 2007
    18. Transdifferentiation of Corneal Epithelium Into Epidermis Occurs by Means of a Multistep Process Triggered by Dermal Developmental Signals Proceedings of the National Academy of Sciences · 2005
    19. Morpho-Regulation of Ectodermal Organs ˜The œAmerican journal of pathology · 2004
    20. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    21. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003
    22. Molecular Biology of Hair Morphogenesis: Development and Cycling Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution · 2003
    23. Control of Pelage Hair Follicle Development and Cycling by Complex Interactions Between Follistatin and Activin The FASEB Journal · 2003
    24. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002