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GlossarymiR-222

small RNA molecule regulating gene expression and hair growth

miR-222 is a type of microRNA, which are small molecules that help regulate gene expression in cells. Specifically, miR-222 has been found to play a role in various biological processes, including cell growth, differentiation, and apoptosis (programmed cell death). In the context of hair and alopecia, miR-222 can influence hair follicle cycling and has been implicated in conditions like androgenetic alopecia, where it may contribute to hair loss by affecting the growth phase of hair follicles.

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The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

research The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

3 citations, February 2022 in “Frontiers in cell and developmental biology”

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

research Neural Progenitor Cell-Derived Nanovesicles Promote Hair Follicle Growth via miR-100

August 2020 in “Research Square (Research Square)”

Neural progenitor cell-derived nanovesicles help hair growth by activating a key signaling pathway.

research Hair Shaft miRNA-221 Levels as a New Tumor Marker of Malignant Melanoma

7 citations, December 2014 in “Journal of dermatology”

Hair shaft miR-221 levels can help detect malignant melanoma.

research Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle

149 citations, June 2010 in “The FASEB journal”

miR-31 regulates hair growth by controlling gene expression in hair follicles.

research Detection of Hair MicroRNAs as Novel Potent Biomarkers: Evaluation of Usefulness for Scleroderma Diagnosis

39 citations, November 2013 in “Journal of dermatological science”

Hair microRNAs could be effective biomarkers for diagnosing scleroderma.

Differential Expression Analysis of Balding and Nonbalding Dermal Papilla MicroRNAs in Male Pattern Baldness Using a MicroRNA Amplification Profiling Method

research Differential Expression Analysis of Balding and Nonbalding Dermal Papilla MicroRNAs in Male Pattern Baldness Using a MicroRNA Amplification Profiling Method

29 citations, March 2012 in “British Journal of Dermatology”

Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.

research The Role of MicroRNA, Long Non-Coding RNA, and Circular RNA in the Pathogenesis of Polycystic Ovary Syndrome: A Literature Review

1 citations, January 2024 in “International journal of molecular sciences”

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

research Wound Healing and the Use of Medicinal Plants

170 citations, September 2019 in “Evidence-based Complementary and Alternative Medicine”

Some medicinal plants can help heal wounds and may lead to new treatments.

research Control by a Hair’s Breadth: The Role of MicroRNAs in the Skin

41 citations, September 2012 in “Cellular and Molecular Life Sciences”

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

research Identification of Ultraviolet B Radiation-Induced MicroRNAs in Normal Human Dermal Papilla Cells

18 citations, July 2014 in “Molecular Medicine Reports”

UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.

research Exosomes as a Novel Pathway for Regulating Development and Diseases of the Skin

15 citations, January 2018 in “Biomedical Reports”

Exosomes are important for skin health and could help diagnose and treat skin diseases.

Epigallocatechin-3-Gallate Inhibits Paclitaxel-Induced Apoptosis Through the Alteration of MicroRNA Expression in Human Dermal Papilla Cells

research Epigallocatechin-3-Gallate Inhibits Paclitaxel-Induced Apoptosis Through the Alteration of MicroRNA Expression in Human Dermal Papilla Cells

3 citations, February 2018 in “Biomedical dermatology”

Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.

research Recent Progress in the Effect of Ferroptosis of Hepatic Stellate Cells on the Development of Liver Fibrosis

2 citations, September 2023 in “Frontiers in molecular biosciences”

Inducing ferroptosis in hepatic stellate cells is crucial for treating liver fibrosis.

research Regenerative Potential and Clinical Application of Mesenchymal Stem Cell-Derived Exosomes

November 2023 in “Klìtinna ta organna transplantologìâ”

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

research Signaling Pathways and Targeted Therapeutic Strategies for Polycystic Ovary Syndrome

October 2023 in “Frontiers in endocrinology”

Effective PCOS treatments require targeting specific signaling pathways.

research Evaluating the Role of lncRNAs in the Incidence of Cardiovascular Diseases in Androgenetic Alopecia Patients

May 2022 in “Cardiovascular Toxicology”

research Identification of Potential Biomarkers for Diagnosis of Patients with Methamphetamine Use Disorder

2 citations, May 2023 in “International Journal of Molecular Sciences”

Gene expression in hair follicles can help diagnose methamphetamine use disorder.

research MicroRNA in Skin Diseases

27 citations, July 2017 in “European Journal of Dermatology”

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

research Biochemistry of Epidermal Stem Cells

26 citations, February 2013 in “Biochimica et Biophysica Acta (BBA) - General Subjects”

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

research Integrated miRNA and mRNA Analysis Provides New Insight into Mechanism of Dermal Papilla in Androgenetic Alopecia

June 2024 in “Research Square (Research Square)”

Increased cell death and reduced cell growth in hair follicles contribute to baldness.

research MSCs and Their Exosomes: A Rapidly Evolving Approach in the Context of Cutaneous Wound Therapy

25 citations, December 2021 in “Stem Cell Research & Therapy”

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

research MicroRNAs in the Skin: Role in Development, Homeostasis, and Regeneration

31 citations, July 2017 in “Clinical Science”

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

research MicroRNA/mRNA Regulatory Networks in the Control of Skin Development and Regeneration

56 citations, February 2012 in “Cell Cycle”

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes

research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes

54 citations, November 2017 in “Scientific Reports”

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Post-Transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation, and Hair Follicle Regression by miR-22

research Post-Transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation, and Hair Follicle Regression by miR-22

52 citations, May 2015 in “PLOS Genetics”

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

research LncRNA-XIST Promotes Dermal Papilla Induced Hair Follicle Regeneration by Targeting miR-424 to Activate Hedgehog Signaling

11 citations, March 2020 in “Cellular Signalling”

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

N6-Methyladenosine Modification of circRNA-ZNF638 Contributes to the Induced Activation of SHF Stem Cells Through miR-361-5p/Wnt5a Axis in Cashmere Goats

research N6-Methyladenosine Modification of circRNA-ZNF638 Contributes to the Induced Activation of SHF Stem Cells Through miR-361-5p/Wnt5a Axis in Cashmere Goats

2 citations, April 2023 in “Animal Bioscience”

A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.

research MiR-23b and MiR-133 Cotarget TGFβ2/NOTCH1 in Dermal Fibroblasts and Affect Hair Follicle Development in Sheep

August 2023 in “Research Square (Research Square)”

Two microRNAs affect hair follicle development in sheep by targeting specific genes.

research LncRNA-599547 Contributes to the Inductive Property of Dermal Papilla Cells in Cashmere Goats Through miR-15b-5p/Wnt10b Axis

7 citations, August 2020 in “Animal biotechnology”

A specific RNA in cashmere goats helps improve hair growth by interacting with certain molecules.

research CircRNA-1926 Promotes Differentiation of Goat SHF Stem Cells into Hair Follicle Lineage by miR-148a/b-3p/CDK19 Axis

16 citations, September 2020 in “Animals”

circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.