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    Glossary miR-222

    small RNA molecule regulating gene expression and hair growth

    miR-222 is a type of microRNA, which are small molecules that help regulate gene expression in cells. Specifically, miR-222 has been found to play a role in various biological processes, including cell growth, differentiation, and apoptosis (programmed cell death). In the context of hair and alopecia, miR-222 can influence hair follicle cycling and has been implicated in conditions like androgenetic alopecia, where it may contribute to hair loss by affecting the growth phase of hair follicles.

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    1. Exosomal miR-222-3p derived from dermal papilla cells inhibits melanogenesis in melanocytes by targeting SOX10 in rabbits Animal Bioscience · 2024
    2. COVID-19 Infection Induce miR-371a-3p Upregulation Resulting in Influence on Male Fertility Biomedicines · 2022 · 6 citations
    3. Integrated Multi-Omics Analysis Reveals Dysregulated Lipid Metabolism as a Novel Mechanism in Androgenetic Alopecia Biomedicines · 2026
    4. MicroRNA-205 promotes hair regeneration by modulating mechanical properties of hair follicle stem cells Proceedings of the National Academy of Sciences · 2023 · 11 citations
    5. MicroRNA/mRNA regulatory networks in the control of skin development and regeneration Cell Cycle · 2012 · 56 citations
    6. The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits 2020 · 3 citations
    7. The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits 2020 · 2 citations
    8. Hair Dermal papilla maintain its hair inducing characteristics via autocrine exosomal miR-23a-3p 2025
    9. The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits 2020
    10. Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes Scientific Reports · 2017 · 54 citations
    11. Hair shaft miRNA‐221 levels as a new tumor marker of malignant melanoma Journal of dermatology · 2014 · 7 citations
    12. MicroRNA in skin diseases European Journal of Dermatology · 2017 · 27 citations
    13. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    14. Systematic Analysis of Non-coding RNAs Involved in the Angora Rabbit (Oryctolagus cuniculus) Hair Follicle Cycle by RNA Sequencing Frontiers in genetics · 2019 · 35 citations
    15. CircRNA-1926 Promotes the Differentiation of Goat SHF Stem Cells into Hair Follicle Lineage by miR-148a/b-3p/CDK19 Axis Animals · 2020 · 16 citations
    16. MiR-23b and miR-133 Cotarget TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development Cells · 2024 · 4 citations
    17. The intragenic mRNA-microRNA regulatory network during telogen-anagen hair follicle transition in the cashmere goat Scientific Reports · 2018 · 13 citations
    18. Liposomal Helix aspersa Snail Mucus: A Biomacromolecular Platform for Attenuating Chronological Skin Aging Through Modulation of miR-34a-Associated Senescence and Extracellular Matrix Remodeling International Journal of Molecular Sciences · 2026
    19. Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway Frontiers in Cell and Developmental Biology · 2026
    20. Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting circ_0135062/miR-506-3p/Bax Axis Aesthetic Plastic Surgery · 2024
    21. Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation through the Chi-miR-214-3p/β-Catenin Axis in Cashmere Goats International journal of molecular sciences · 2022 · 7 citations
    22. Melatonin Regulates the Proliferation of Liaoning Cashmere Goat Skin Fibroblasts via the lncRNA16913.1-chi-miR-195-5p-FZD6 Axis Animals · 2026
    23. Identification of the Keratin-Associated Protein 22-2 Gene in the Capra hircus and Association of Its Variation with Cashmere Traits Animals · 2023 · 1 citations
    24. Integrative analysis reveals ncRNA-mediated molecular regulatory network driving secondary hair follicle regression in cashmere goats BMC Genomics · 2018 · 50 citations
    25. Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle ˜The œFASEB journal · 2010 · 149 citations
    26. Study on the regulatory effect of Panax notoginseng saponins combined with bone mesenchymal stem cell transplantation on IRAK1/TRAF6-NF-κB pathway in patients with diabetic cutaneous ulcers Journal of Orthopaedic Surgery and Research · 2023 · 10 citations
    27. Multi-omics and AI-driven advances in miRNA-mediated hair follicle regulation in cashmere goats Frontiers in Veterinary Science · 2025 · 2 citations
    28. MicroRNA-181a Targets GNAI2 and Affects the Proliferation and Induction Ability of Dermal Papilla Cells: The Potential Involvement of the Wnt/β-Catenin Signaling Pathway International Journal of Molecular Sciences · 2024 · 1 citations
    29. The Role of MicroRNA, Long Non-Coding RNA and Circular RNA in the Pathogenesis of Polycystic Ovary Syndrome: A Literature Review International journal of molecular sciences · 2024 · 1 citations
    30. Biological Function of Long Non-coding RNA (LncRNA) Xist Frontiers in Cell and Developmental Biology · 2021 · 247 citations