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The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Mobile phone radiation may cause DNA damage in human ear hair follicle cells.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Microneedling with 5% minoxidil improves hair loss in Chinese men by activating Wnt/ß-catenin pathway.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Gray hair can potentially be reversed, leading to new treatments.

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Effective PCOS treatments require targeting specific signaling pathways.

Certain long non-coding RNAs are important for controlling hair growth cycles in sheep.

JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

New therapies are being developed that target integrin pathways to treat various diseases.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

Adipose-derived stem cells help heal burns but need more research.

PRP helps skin heal, possibly through special cells called telocytes.