TLDR Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.
The document discusses the potential of cell and cell-free therapies in treating osteoarthritis. It emphasizes the role of mesenchymal stem cells (MSCs) and adipose-derived stem cells (ADSCs) in promoting cartilage regeneration and slowing osteoarthritis progression. The use of platelet-rich plasma (PRP) in knee osteoarthritis treatment is also mentioned. However, the effectiveness of these therapies can be influenced by factors like the donor's age and the stem cells' source. The document also discusses the use of autologous uncultured adipose-derived stromal cells in inhibiting cartilage degeneration. While these therapies show promise, more research is needed to confirm their safety and efficacy.
19 citations,
August 2019 in “Seminars in Plastic Surgery” Platelet-rich plasma is beneficial in various plastic surgery applications, but more research is needed to standardize its use.
27 citations,
July 2017 in “Facial Plastic Surgery” Platelet-Rich Plasma (PRP) shows promise for hair growth and skin improvement in aesthetic surgery.
316 citations,
June 2017 in “Stem Cell Research & Therapy” Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.
106 citations,
January 2016 in “Journal of Cosmetic Dermatology” Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.
205 citations,
April 2013 in “British Journal of Dermatology” Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.
January 2017 in “Hair transplant forum international” Platelet-rich plasma (PRP) treatments are not effective.
August 2024 in “Journal of Clinical Medicine” PRP shows promise but lacks consistent evidence and regulation.
6 citations,
November 2020 in “Annals of Plastic Surgery” Adipose-derived stem cells and platelet-rich plasma together can protect skin and hair from radiotherapy damage.
6 citations,
June 2020 in “Journal of Drugs in Dermatology” PRP can help regrow hair in people with alopecia.
January 2018 in “Journal of Visualized Experiments” PRP injections significantly increased hair count and density with less pain.
1 citations,
January 2018 in “Revue Médicale de Bruxelles” PRP injections may help with hair loss, but more research is needed.
