2 citations
,
January 2022 in “BioMed Research International” This study found that newly developed nanogels for transdermal delivery of finasteride were stable, showed excellent drug permeation through the skin, and ensured biocompatibility without causing irritation or toxicity.
January 2026 in “International Journal of Applied Pharmaceutics” This review discusses the integration of nanoparticles with microneedles to improve drug delivery through enhanced stability, bioavailability, and controlled release, noting ongoing challenges with stability, scalability, and safety.
353 citations
,
May 2016 in “TrAC Trends in Analytical Chemistry” This review discusses recent advances in droplet microfluidics for chip-based technologies such as single-cell analysis, small-scale cell cultures, and high-throughput drug screening, and it reports no new results.
6 citations
,
January 2016 in “Open journal of regenerative medicine” This study found that macrophages treated with keratin in vitro were more similar to anti-inflammatory M2 macrophages and reduced astrocyte reactivity, potentially limiting secondary inflammatory damage after spinal cord injury.
October 2023 in “Applied materials today” In this study, researchers developed a novel TA-encapsulated microneedle applicator that successfully promoted hair growth and reduced inflammation in a C3H/HeJ mouse model of alopecia areata, potentially offering an improved alternative to existing treatments.
January 2019 in “Research & Reviews: Journal of Pharmaceutics and Nanotechnology” This review discusses polycystic ovary syndrome's metabolic and reproductive impacts, highlighting its insulin resistance and related complications, but reports no new research findings, underscoring the need for lifestyle modifications.
April 2023 in “Journal of Drug Delivery Science and Technology” This study reported that optimized transfersomes and their gel form significantly improved transdermal delivery and hair growth promotion of minoxidil in C57BL/6 mice compared to commercial formulations.
28 citations
,
June 2003 in “Applied immunohistochemistry & molecular morphology” This study demonstrated that combining cell conditioning with mild protease digestion enhanced the visualization of versican mRNA in formalin-fixed mouse skin tissue sections compared to using either technique alone.
January 2020 in “Brazilian Journal of Health and Pharmacy” This study developed nanostructured lipid carriers for finasteride that demonstrated high encapsulation efficiency and reduced cytotoxicity, suggesting potential as a topical treatment for androgenetic alopecia.
2 citations
,
August 2011 in “Dermatologic Surgery” This abstract provides no specific research findings; it appears to contain journal subscription information and other non-research content.
May 2025 in “The Journal of Rheumatology” In this case report, researchers detailed the clinical management and positive outcome of a 62-year-old woman with catastrophic antiphospholipid syndrome associated with systemic lupus erythematosus, highlighting the potential effectiveness of Eculizumab in achieving disease remission and maintaining stability over 18 months.
30 citations
,
April 2009 in “Mycoses” This study found that the fungus Microsporum gypseum enzymatically degrades keratin in human hair, with the sequence of degradation reflecting the keratinization and cystine content of individual hair components in vitro.
60 citations
,
February 1997 in “Journal of Dermatological Science” This study demonstrated that phosphatidylcholine liposomes can deliver calcein and melanin into hair follicles and shafts in mice without significant penetration into the dermis, epidermis, or bloodstream.
January 2014 in “Institutional Repositories DataBase (IRDB)” The study observed that cell spheres formed from mesenchymal cells of newborn mice skin exhibited upregulation of markers linked to hair follicle regeneration, suggesting a potential hibernation-like state for maintaining viability.
January 2021 in “Mastology” This study found that over 80% of women treated with paclitaxel who used a hypothermic glycerin-based hydrogel cap preserved at least 50% of their initial hair volume, suggesting scalp cooling may effectively prevent chemotherapy-induced alopecia.
July 2025 in “Nano Research” This article discusses how designing biomaterials to modulate immune responses has become a promising strategy for enhancing tissue repair and regeneration.
37 citations
,
November 2024 in “Cosmetics” This review examines the promising role of nanocarriers, specifically liposomes and ethosomes, in enhancing transdermal drug delivery for skin diseases. Ethosomes, highlighted for their ability to penetrate deeper skin layers, show potential for more effective treatments but require further clinical investigation.
17 citations
,
February 2025 in “Smart Medicine” In this study, a multifunctional microneedle patch made from silk fibroin-methacryloyl and gelatin methacryloyl was reported to significantly prevent bacterial infection and promote wound healing in vivo due to its antimicrobial silver nanoparticles and VEGF-loaded tips.
7 citations
,
July 2018 in “International Journal of Applied Pharmaceutics” This study found that optimizing chitosan-tripolyphosphate nanoparticles can enhance the sustained percutaneous delivery of caffeine, with certain conditions affecting stability and release rates.
4 citations
,
May 2025 in “International Journal of Nanotechnology and Nanomedicine” This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.
9 citations
,
January 2016 in “Journal of Controlled Release” This study found that applying controlled hypobaric stress to the skin significantly improved the in vitro and in vivo penetration of macromolecules, facilitating enhanced drug delivery.
5 citations
,
April 2024 in “Science China Materials”
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
August 2025 in “Advanced Science” In this study, corrected data confirmed that AHFS seed microspheres exhibit good biocompatibility with fibroblasts, validating the initial results.
April 2024 in “Molecules/Molecules online/Molecules annual” The researchers reported that sulfated chitosan-containing sponges can modulate macrophage activity in diabetic wounds, reducing inflammation and promoting angiogenesis and tissue regeneration, which may enhance wound healing outcomes.
January 2024 in “RSC pharmaceutics” This source discusses using stratum corneum ablation as a promising method to enhance transdermal drug delivery by temporarily removing the skin's outermost barrier to improve medication absorption.
4 citations
,
December 2014 in “Indian Journal of Dermatology” This case report documents a rare presentation of congenital milia en plaque on the scalp of a five-year-old boy, with blaschkoid extension to the nuchal area, highlighting its uncommon location and onset.
1 citations
,
February 2023 in “Pharmaceutics” This study suggests that UVA-responsive nanocapsules may provide an effective method for skin antisepsis by releasing ethanol and reducing microorganisms within hair follicles on ex vivo porcine ear skin.
18 citations
,
October 2016 in “European Journal of Pharmaceutics and Biopharmaceutics” In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.
34 citations
,
October 2021 in “Scientific Reports” This study found that nobiletin-loaded vesicles effectively restored skin condition in a mouse model of skin cancer, suggesting they are a promising treatment delivery system.