Nanoparticle-Embedded Microneedles for Enhanced Transdermal Delivery: Advances and Applications

    January 2026 in “ International Journal of Applied Pharmaceutics ”
    SMRITI MANIBHUSHANAM, Umashankar Marakanam Srinivasan, Damodharan . Narayanasamy
    Studysummary This review discusses the integration of nanoparticles with microneedles to improve drug delivery through enhanced stability, bioavailability, and controlled release, noting ongoing challenges with stability, scalability, and safety.
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    2. Microneedles as Transdermal Drug Delivery System for Enhancing Skin Disease Treatment Acta Pharmaceutica Sinica B · 2024
    3. 3D Printed Microneedles: Revamping Transdermal Drug Delivery Systems Drug Delivery and Translational Research · 2024
    4. Hydrogel Forming Microneedles Loaded With VEGF and Ritlecitinib/Polyhydroxyalkanoates Nanoparticles for Mini-Invasive Androgenetic Alopecia Treatment Bioactive materials · 2024
    5. A Lipid–Polymer Hybrid Nanoparticle-Loaded Dissolving Microneedle Patch for Promoting Hair Regrowth by Transdermal miR-218 Delivery Biomaterials Science · 2022
    6. A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations, and Applications Polymers · 2021
    7. Microneedle Arrays Combined With Nanomedicine Approaches for Transdermal Delivery of Therapeutics Journal of Clinical Medicine · 2021