Dynamic Immunomodulatory Nanoarchitectonics: Rewiring Tissue Regenerative Microenvironment via Intelligent Regulation

    July 2025 in “ Nano Research ”
    H. Y. Yuan, Bowen Li, Xuefei Shao … Bin Zheng
    Studysummary This article discusses how designing biomaterials to modulate immune responses has become a promising strategy for enhancing tissue repair and regeneration.
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    Research cited in this study 15

    1. Micropore structure engineering of injectable granular hydrogels via controlled liquid-liquid phase separation facilitates regenerative wound healing in mice and pigs Biomaterials · 2025
    2. 3D Bioprinting of Engineered Exosomes Secreted from M2-Polarized Macrophages Through Immunomodulatory Biomaterial Promotes In Vivo Wound Healing and Angiogenesis Bioactive Materials · 2024
    3. An ROS-Scavenging Treg-Recruiting Hydrogel Patch for Diabetic Wound Healing Advanced Functional Materials · 2024
    4. Platelet-Rich Plasma in Dermatology: Cellular and Molecular Mechanisms of Action Biomedicines · 2023
    5. Orchestration of Mesenchymal Stem/Stromal Cells and Inflammation During Wound Healing Stem Cells Translational Medicine · 2023
    6. New Insights Into Balancing Wound Healing And Scarless Skin Repair Journal of Tissue Engineering · 2023
    7. Macrophages in Skin Wounds: Functions and Therapeutic Potential Biomolecules · 2022
    8. Engineering Immunomodulatory Biomaterials to Drive Skin Wounds Toward Regenerative Healing Cold Spring Harbor Perspectives in Biology · 2022
    9. Platelet Therapeutics to Improve Tissue Regeneration and Wound Healing: Physiological Background and Methods of Preparation Biomedicines · 2021
    10. Mechanical and Immunological Regulation in Wound Healing and Skin Reconstruction International Journal of Molecular Sciences · 2021
    11. Diverse Cellular Players Orchestrate Regeneration After Wounding Experimental Dermatology · 2020
    12. The Dynamics of the Skin’s Immune System International Journal of Molecular Sciences · 2019
    13. Stem Cell Dynamics, Migration, and Plasticity During Wound Healing Nature Cell Biology · 2018
    14. Wound Healing: A Cellular Perspective Physiological Reviews · 2018
    15. Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration Frontiers in Immunology · 2018