Dissecting the Microenvironment Around Biosynthetic Scaffolds in Murine Skin Wound Healing
May 2021
in “
Science Advances
”
biosynthetic scaffolds wound healing immune responses electrospun membranes aligned scaffolds adaptive immunity fibrotic response T lymphocytes hair neogenesis hair follicle regeneration single-cell RNA sequencing extracellular matrix formation macrophage subsets T cell populations scaffolds immune response membranes fibrosis T cells hair growth RNA sequencing extracellular matrix macrophages
Studysummary In this study, researchers found that electrospun membranes with aligned surface topography advanced the immune response towards an adaptive stage and highlighted the role of T cells in hair follicle regeneration in mice, showcasing the intricate interactions between immune and skin cells.
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