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In this review, researchers summarized findings from clinical studies on mesenchymal stem cells for diabetes treatment, noting their potential but also highlighting challenges like small sample sizes and the need for standardization in preparation and delivery methods.

This study explored how high glucose concentrations impact mesenchymal stromal cell survival in diabetic environments, highlighting mitochondrial factors as potential targets for enhancing cell viability.

This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.

This study identified a comprehensive global landscape of stemness-related gene clusters in adipose-derived mesenchymal stem cells, revealing that stemness was highest in cells from young donors and lowest in those from elderly donors.

This study found that mesenchymal stem cells showed potential to differentiate into hair follicle stem cells when induced by the supernatant of cultured hair follicles in vitro.

This article provides an overview of mesenchymal stem cells, highlighting their extraction methods, differentiation potential, and applications in regenerative medicine, but reports no new clinical findings.

This review discusses the paracrine function of mesenchymal stem cells in tissue regeneration and repair, focusing on secreted bioactive substances and their role under different microenvironments; it reports no new clinical results.

This review discusses the therapeutic potential of mesenchymal stem cell-derived small extracellular vesicles for chronic wound treatment and reports no new clinical results, emphasizing the need for further research on their large-scale production and engineering.

This study identified a distinct CD49fhigh mesenchymal stem cell subpopulation in the dermis that supports hair follicle development and maintenance via Notch signaling activation.

This review discusses the potential of mesenchymal stem cells and their secretome as promising therapeutic tools for systemic lupus erythematosus but reports no new clinical results.

In this study, the authors observed that the combined treatment group showed a significant increase in inflammatory cell density and a higher maximum tensile breaking force in tendon repair by the end of the second month.

This study demonstrated that autologous mesenchymal stem cells from hair follicles, when combined with a novel gelatin-based hydrogel, showed promising osteogenic potential and could offer a non-invasive alternative for bone regeneration.

In this review, researchers discussed the potential of mesenchymal stem cells and their exosomes as a promising therapy for burn injuries, emphasizing their role in inflammation regulation, tissue regeneration, and overcoming challenges in clinical translation, but noting obstacles in standardization and quality control.

This study found that bone marrow mesenchymal stem cells promoted faster wound healing and thicker epidermis in rabbit skin wounds, suggesting they can differentiate into epidermal cells and aid regeneration.

This study found that hair follicle-derived dermal stem cells and bone marrow mesenchymal stem cells have similar growth, differentiation capabilities, and surface marker expressions, suggesting hair follicles could be accessible sources for mesenchymal stem cells.

This review discusses the potential of mesenchymal stem cells from the oral cavity for tissue regeneration in oral and maxillofacial surgery but reports no new clinical results.

This review evaluates methods to study stem cell division patterns, particularly in the mammary gland, and discusses genetic factors affecting division modalities and their implications for breast cancer, but reports no new results.

This review examines various methods to enhance the functionality and therapeutic potential of mesenchymal stem cells for clinical use, highlighting both advancements and ongoing limitations, without presenting new clinical results.

This review discusses the potential role of mesenchymal stromal cell-derived exosomes in skin regeneration and calls for more research to address clinical translation challenges, without reporting new results.

This study found that exosomes from different mesenchymal stem cell sources had distinct effects on immune cell functions and varied microRNA expression profiles compared to their original cells.

This review summarizes the mechanisms of mesenchymal stem cell-mediated wound healing and highlights engineering strategies that enhance therapeutic outcomes, but it reports no new clinical results.

This review discusses recent preclinical strategies for enhancing mesenchymal stem cell delivery to ischemic cardiac and peripheral tissues but reports no clinical results.

This review suggests that mesenchymal stem cells' therapeutic effects might be due to bioactive substances they release, rather than the cells themselves, highlighting the potential of the MSC secretome as a novel, cell-free therapeutic approach.

This study found that explant transfers of human umbilical cord Wharton's jelly-derived mesenchymal stem cells can yield cells for five consecutive times, optimizing primary cell production and reducing costs.

This study found that human bone marrow mesenchymal stem cell-derived exosomes promote cutaneous wound healing in rats by inhibiting the TGF-β/Smad signaling pathway.

This review discusses the processes of melanocyte stem cell quiescence and activation, focusing on their interaction with hair follicle stem cells, and highlights current research on hair graying mechanisms; it reports no new results.

This study reports that in mesenchymal cells, the effect of resveratrol on cell viability and metabolic enzyme activity varied with dosage and exposure time, with high doses promoting bone differentiation and potentially benefiting mesenchymal cell health and differentiation into osteoblasts.

This study in adult male albino rats reported that human umbilical cord blood-derived mesenchymal stem cells were more effective than minoxidil in promoting hair growth for androgenic alopecia, observing superior outcomes in hair follicle metrics.

In this study, secretomes from hypoxic mesenchymal stem cells were found to increase PDGF and reduce IL-1β gene expression in rats, potentially offering an effective topical treatment for alopecia caused by long-term fluconazole use.

This study found that exosomes derived from human bone marrow mesenchymal stem cells significantly promote cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.