Mesenchymal Stem Cells from Mouse Hair Follicles Inhibit the Development of Type 1 Diabetes

May 2024 in “ International Journal of Molecular Sciences ”

Dragica Mićanović, Suzana Stanisavljević, Hanluo Li, Ivan Koprivica, Natalija Jonić, Ivana Stojanović, Vuk Savković, Tamara Saksida

mesenchymal stem cells hair follicles cytokines immune responses regulatory T cells Th17 cells CD8+ T cells

Studysummary This study found that injecting mouse hair follicle-derived mesenchymal stem cells (moMSCORS) into C57BL/6 mice reduced the incidence and severity of type 1 diabetes by modulating immune responses, suggesting potential for therapeutic use due to their immunosuppressive effects.

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research Mesenchymal Stem Cells Isolated From Equine Hair Follicles Using A Method Of Air-Liquid Interface

September 2023 in “Stem cell reviews and reports”

This study introduces a new method to isolate stem cells from the hair follicle outer root sheath of equine skin, demonstrating that these cells, named eMSCORS, proliferate efficiently and can differentiate similarly to adipose tissue-derived MSCs, offering a promising alternative for equine veterinary applications.

research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model

13 citations , January 2022 in “Stem cell reviews and reports”

This study found that using cultured mesenchymal stem cells from mouse whisker hair follicle outer root sheath in wound healing reduced inflammation, accelerated closure, and resulted in less hypertrophic scarring in mice.