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Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

OR2AT4 helps reduce aging and cell damage in human skin cells.

Shampoo with heat-killed Lacticaseibacillus paracasei GMNL-653 improves scalp health and hair growth by changing scalp bacteria.

Androgen use may increase the risk of stroke, but more research is needed.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

Male and female pattern hair loss have different molecular pathways, suggesting unique treatment targets for each sex.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Metabolites and diet affect hair growth cycles in cashmere goats.

High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.

The study concluded that the arachidonic acid pathway and the protein KRT79 play a role in determining the fineness of cashmere.

Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.

Lipids from Schizochytrium sp. help prevent hair loss by protecting hair cells from damage and promoting hair growth.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

More research is needed to understand how testosterone is maintained in adult males.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

More precise, personalized therapies are needed for autoimmune diseases.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Endocannabinoids help control mast cell activity in human skin.