This study found that urinary and serum selenium levels were the most sensitive biomarkers for selenium intake in adult dogs, with serum GPx responding more quickly than whole blood GPx.
August 2019 in “International journal of current microbiology and applied sciences” This study found that among 86 skin scrapings from various dog breeds with ringworm lesions, Microsporum species were the predominant fungal infection, with Labradors showing the highest infection rate. Miconazole was most effective in antifungal susceptibility tests.
January 1983 in “Journal of the Japan Veterinary Medical Association” This case study of a toy poodle with Cushing syndrome found that after unsuccessful initial treatments, hair growth and symptom alleviation occurred following daily administration of o,p'-DDD, despite initial side effects.
July 2023 in “Jurnal Ilmu Kesehatan Hewan” In this case report, a 2-month-old dog with scabies showed improvement in skin condition and reduced mite presence 24 days after treatment with simparica, sulfur-based soap, and various topical and oral therapies.
October 2025 in “Journal of Veterinary Clinics” In this case study, a Pomeranian was diagnosed with vaccine-induced ischemic dermatopathy, where different medication regimens gradually improved hair regrowth, though some lesions persisted after tapering treatment.
18 citations
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October 2017 in “PLOS ONE” This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.
This study introduces Kalya Research, an AI-driven tool designed to identify and categorize literature on complementary and alternative medicines, showing its effectiveness compared to Medline in finding relevant alopecia research within the context of breast cancer patients.
January 2020 in “Animal Husbandry Dairy and Veterinary Science” This case report describes a Labrador retriever with arthrosis whose symptoms improved after sequential treatments including corticosteroids and tetracycline, leading to the resolution of dermatitis and nodular tumors.
March 2026 in “Buletin Veteriner Udayana” In this case report, a 3-month-old puppy with Malassezia dermatitis showed substantial improvement and complete recovery from pruritus, skin lesions, and hair loss after four weeks of treatment with Sebazole® shampoo, apple cider vinegar, virgin coconut oil, and diphenhydramine.
July 2026 in “Buletin Veteriner Udayana” In this case report, combination therapy effectively resolved chronic malasseziosis within 28 days in a small-breed dog from a Southeast Asian tropical climate, with significant symptom improvement and reduced Malassezia density observed by week 4.
May 2023 in “MQRInvestigar” In this case study, a 3-year-old German Shepherd treated for an enlarged prostate with medication and surgery showed a significant prostate size reduction by 93.9% over 138 days, ruling out neoplastic processes.
July 2025 in “Veterinary Parasitology Regional Studies and Reports” This study found that both oral afoxolaner (NexGard®) and topical Frontline Combo® achieved 100% efficacy in eradicating Heterodoxus spiniger infestations within 30 days in dogs, with significant reductions in associated symptoms like hair loss and pruritus.
1 citations
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November 2022 in “PubVet” This case study describes using microneedling combined with orchiectomy as a treatment for alopecia X in a male German Spitz dog, highlighting this approach for managing the condition.
March 2024 in “American journal of veterinary research” This study found that clippers are the safest and most efficient tool for collecting hair samples from companion dogs, with no impact on cortisol concentration compared to scissors.
January 2024 in “Editora In Vivo eBooks” In this case report, a dog was diagnosed with dermatophytosis, a zoonotic fungal infection common in humid climates, presenting with alopecia in the neck and ear regions.
April 2021 in “Cermin Dunia Kedokteran” This study reports improvement in tinea capitis symptoms in two siblings after two months of treatment with ketoconazole lotion and shampoo, following initial findings of M. canis and Rhodotorulla infections.
18 citations
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January 2013 in “Veterinary Dermatology” This study found that K15 is a useful marker for investigating the role of stem cells in canine hair follicle tumours, while nestin is not optimal.
January 2024 in “Jurnal Ilmu Kesehatan Hewan” In this study, a two-month-old dog diagnosed with scabiosis and toxocariosis showed significant clinical improvement after being treated with sarolaner and pyrantel, evidenced by resolved skin lesions, hair regrowth, and a return to normal abdominal size and oral mucosa color after 30 days.
15 citations
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March 2019 in “Veterinary Dermatology” This study found that three mousse products containing chlorhexidine and varying antifungal components maintained significant antibacterial activity against S. pseudintermedius in vitro for up to 10 days, while other mousses did not show significant differences.
4 citations
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June 2024 in “Animals” This study found that treating dogs with benign prostatic hyperplasia using osaterone acetate reduced prostatic volume and increased diffusion times of an ultrasound contrast agent, suggesting effective treatment and potential for CEUS monitoring.
5 citations
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February 2015 in “Journal of Comparative Pathology” This study suggests that high proliferative activity and peripheral invasion are key indicators of malignancy in canine sebaceous gland tumours. It also reports a higher incidence of circumanal gland and testicular tumours, indicating a possible androgen-related pathway in tumour development.
4 citations
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November 2018 in “Journal of comparative pathology” This study found that adipokines were expressed in the epidermis, hair follicles, sebocytes, apocrine glands, and vascular endothelium of normal canine skin, but not in the dermis or hypodermis.
January 2025 in “Seven Editora eBooks” In this study, the authors reported a case of alopecia X in a German Spitz dog and found that treatment with orchiectomy and melatonin resulted in partial hair regrowth and improved the dog's dermatological condition.
21 citations
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July 2006 in “Veterinary dermatology” In this study, researchers reported that CD34 expression in the isthmic region of canine hair follicles suggests a potential stem cell compartment in this area.
34 citations
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July 2018 in “Veterinary Dermatology” This study established a 3D in vitro culture system of canine keratinocyte organoids to study epidermal function and address skin disorders in dogs, though additional growth factors are needed for hair follicle development.
11 citations
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January 2016 in “BMC veterinary research” This study found that urinary selenium to creatinine ratio and serum selenium concentrations quickly respond to changes in dietary selenium, making them useful biomarkers for assessing selenium status in dogs.
2 citations
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April 2016 in “Veterinary dermatology” This study found that a 2% climbazole shampoo had significant residual antifungal activity on beagle hair shafts, which increased after subsequent use of a physiological shampoo.
August 2004 in “Veterinary Dermatology” This study found that hair loss in Chesapeake Bay retrievers may be related to abnormal production of adrenal sex hormones, with further research needed to explore its heritability and treatment options.
June 2024 in “Indian Journal of Veterinary Medicine” In this case report, a one-year-old male dog with demodicosis, confirmed by the presence of Demodex canis and Staphylococcus bacteria, was successfully treated using ivermectin, amitraz, cephalexin, and vitamin supplements with liver extract.
This study found that hair and nails can effectively measure hormone changes such as testosterone, estrogen, and progesterone during the peripubertal period in dogs, with variations observed between males and females at specific developmental stages.