18 citations
,
January 2013 in “Veterinary Dermatology” K15 is a reliable marker for studying stem cells in dog hair follicle tumors.
6 citations
,
March 2011 in “European Journal of Dermatology” Nestin-positive cells are important for hair follicle regeneration in alopecia areata.
35 citations
,
December 2008 in “PubMed” Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.
276 citations
,
January 2005 in “International review of cytology” More research is needed to understand how hair keratins work and their role in hair disorders.
199 citations
,
January 2004 in “The International Journal of Developmental Biology” Hair follicle growth and development are controlled by specific genes and molecular signals.
29 citations
,
April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
10 citations
,
October 2000 in “PubMed” The study investigated the effects of expressing human papillomavirus type 16 E6/E7 oncogenes in the outer root sheath of hair follicles in transgenic mice. These mice exhibited a fur phenotype with lower hair density but faster hair regeneration compared to wild-type mice. The expression of these oncogenes extended the growth phase (anagen) of hair follicles and bypassed the resting phase (telogen), leading to continuous hair follicle cycling. Although the first hair growth cycle appeared normal, the second cycle showed delayed initiation of catagen and insensitivity to telogen resting signals, even with estradiol present. This indicated that E6/E7 expression in the ORS delayed catagen entry and prevented telogen rest, resulting in ongoing hair follicle cycling.
94 citations
,
February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” EGF makes hair follicles grow longer but stops hair production.
135 citations
,
November 1987 in “Differentiation” Outer root sheath cells consistently express certain keratins influenced by their environment.
