Microneedling Associated with Orchiectomy as a Treatment for Alopecia X in a German Spitz Dog

November 2022 in “ PubVet ”

Fernanda Letícia de Aguiar Mello, Virgínia Paula Couto Vigas Sodré, Humberto Santos da Silva, Antônio Fernando Uzêda Sodré

microneedling orchiectomy alopecia X German Spitz Nordic breeds double coats dermatopathy

TLDR Microneedling and orchiectomy helped treat hair loss in a German Spitz dog.

This study reported a case of a male German Spitz dog with alopecia X, a non-inflammatory and non-pruritic dermatopathy common in Nordic breeds with double coats. The therapeutic approach combined microneedling with orchiectomy. Alopecia X was characterized by gradual hair loss, sparing only the head and the distal parts of the limbs in advanced stages. The etiology and pathogenesis of alopecia X remained unclear, but there were indications of genetic factors associated with the disease.

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research Microneedling Associated with Orchiectomy as a Treatment for Alopecia X in a German Spitz Dog

1 citations , November 2022 in “PubVet”

Microneedling and orchiectomy helped treat hair loss in a German Spitz dog.

research Novel Insights Into the Pathways Regulating the Canine Hair Cycle and Their Deregulation in Alopecia X

18 citations , October 2017 in “PLOS ONE”

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.

research Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model

55 citations , January 2016 in “Annals of Dermatology”

Microneedle stimulation can increase hair growth in mice.

research Microneedling as a Successful Treatment for Alopecia X in Two Pomeranian Siblings

12 citations , July 2015 in “Veterinary Dermatology”

Microneedling helped two Pomeranian dogs with a hair growth disorder grow back 90% of their fur in 12 weeks, and the results lasted for a year.

research Canine Noninflammatory Alopecia: A Comprehensive Evaluation of Common and Distinguishing Histological Characteristics

28 citations , May 2012 in “Veterinary Dermatology”

Different types of dog hair loss are linked to problems starting the hair growth phase and early hair cycle ending.

research Estrogen Receptor Evaluation in Pomeranian Dogs with Hair Cycle Arrest (Alopecia X) on Melatonin Supplementation

20 citations , July 2006 in “Veterinary dermatology”

Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.

research Treatment of Canine Alopecia X with Trilostane

40 citations , October 2004 in “Veterinary Dermatology”

Trilostane treatment led to full hair regrowth in most Pomeranians and all miniature poodles with alopecia X.

Adrenal Steroid Hormone Concentrations in Dogs with Hair Cycle Arrest (Alopecia X) Before and During Treatment with Melatonin and Mitotane

research Adrenal Steroid Hormone Concentrations in Dogs with Hair Cycle Arrest (Alopecia X) Before and During Treatment with Melatonin and Mitotane

52 citations , October 2004 in “Veterinary dermatology”

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

research Retrospective Evaluation of Sex Hormones and Steroid Hormone Intermediates in Dogs with Alopecia

34 citations , March 2003 in “Veterinary Dermatology”

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.