Efficacy of Oral Afoxolaner (NexGard®) Against Natural Infestations with Heterodoxus Spiniger (Phthiraptera: Boopiidae) in Dogs Under Field Conditions

    July 2025 in “ Veterinary Parasitology Regional Studies and Reports ”
    Andrei Daniel Mihalca, SS Lolokote, Akpesse Akpa Alexandre Moïse, David Modrý, F. Beugnet
    TLDR NexGard® and Frontline Combo® are both 100% effective at eliminating lice in dogs.
    The study evaluated the efficacy of oral afoxolaner (NexGard®) against Heterodoxus spiniger infestations in dogs, comparing it to a topical ectoparasiticide (Frontline Combo®). Conducted in Kenya with 36 dogs, the study found that both treatments achieved 100% efficacy in eradicating lice by day 30, with no reinfestation observed. Significant improvements in hair loss, pruritus, and scaling were noted in both groups by days 15 and 30. The results demonstrate that both NexGard® and Frontline Combo® are highly effective against H. spiniger in dogs.
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