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This study found that keratinocytes derived from the germinative epithelium of ovine hair follicles have extensive in vitro growth potential, challenging the idea that these cells are solely transit-amplifying.

This review discusses autologous dermis-derived stem cells and their potential in regenerative medicine, summarizing current literature on their niches, characteristics, and applications, but it reports no new experimental results.

This review summarizes recent research on the therapeutic uses of adipose-derived stem cells for wound healing and treating skin diseases but does not provide new experimental results.

In this research, authors found that skin-resident ILCs regulate sebaceous gland function and microbial balance, emphasizing an immune-epithelia system that supports host-microbe symbiosis.

This study found that in mice, epidermal Wnt/β-catenin signaling influences adipocyte differentiation and hair growth, suggesting its critical role in synchronizing adipogenesis with the hair growth cycle.

This review discusses various gene therapy and non-viral delivery methods to promote angiogenesis for chronic wound healing, but it reports no new clinical results.

In this study, researchers found that hair follicle stem cells activate an immune-modulatory program during wound healing, promoting Treg cell expansion and aiding skin repair, while deleting certain immune components impaired healing and increased inflammation in a mouse model.

This study found that control of Demodex mite colonization in mice required skin ILC2s and IL-13, highlighting their role in maintaining HF integrity and limiting mite overgrowth.

This review discusses the potential of fibrinolytic enzymes from various sources, especially fermented foods, for their therapeutic use in cardiovascular diseases and emphasizes the need for further research on those from non-Asian regions to optimize discovery and application.

This study found that 3D spheroid culture reprogrammed mesenchymal stem cells into a uniform immunosuppressive phenotype, suggesting potential therapeutic applications for inflammatory diseases like psoriasis.

This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.

This study found that deleting podoplanin in mouse keratinocytes promoted hair follicle growth during regeneration, suggesting it may regulate hair cycling pathways that could aid in treating hair loss conditions.

This study conducted a genome-wide analysis in Tianzhu white yaks, identifying differential genes associated with hair growth between long-haired and normal-haired individuals.

This study found that DNMT1 promotes adipogenesis in hair follicle stem cells by regulating the miR-214-3p/MAPK1/p-ERK1/2 pathway, suggesting potential applications in stem cell therapy.

This study identified genetic loci and pathways associated with long hair growth in the Tianzhu white yak, providing new insights into the genetic mechanisms of this trait.

This study mapped gene expression in different skin structures of dogs, finding similarities to humans that support using dogs as models for human skin diseases.

This study found that wounds in sheep treated with mesenchymal stem cells and platelet-rich plasma showed improved healing, reduced inflammation and contraction, and better skin structure compared to untreated wounds.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.

This study suggests that novel diagnostic, preventive, and treatment approaches for autoimmune diseases like alopecia areata may be developed by identifying hub genes, and highlights the usefulness of machine learning and bioinformatics in finding new disease biomarkers.

This study demonstrated that autologous mesenchymal stem cells from hair follicles, when combined with a novel gelatin-based hydrogel, showed promising osteogenic potential and could offer a non-invasive alternative for bone regeneration.

This study found that PBMCsec has anti-fibrotic effects on mouse and human skin scars by regulating pro-fibrotic gene expression and inhibiting myofibroblast differentiation and elastic fiber breakdown.

This study found that in Lichen Planopilaris, the Microbacteriaceae family was negatively correlated with IL-23 expression, suggesting a role in the disease's inflammation and microbiota composition.

This research observed that translation initiation shifts from cap-dependent to IRES-mediated pathways varied across tissues and cell types under stress and differentiation conditions in mice, with low IRES/Cap ratios signaling high stemness and potential multipotency, mediated by the RNA processing protein PTBP1.

This study observed that the loss of H3K9me3, via the ablation of Suv39h1, Suv39h2, and Setdb1 in embryonic mouse epidermis, disrupts skin development processes such as keratinocyte differentiation and hair follicle formation, highlighting H3K9me3's crucial role in epidermal morphogenesis.

In this study, genetic factors associated with hirsutism were identified, suggesting that both androgen-dependent and independent mechanisms may contribute to excessive hair growth in women.

This study found that late embryonic skin injuries can regenerate multiple tissue types, but this ability is hindered postnatally due to fibroblast-driven hyperinnervation, which can be mitigated to enable regeneration.

In this study, researchers developed a DNA/GelMA-based cryogel platform that uses phototherapy to combat MRSA infection and promote scarless wound healing, showing enhanced bactericidal activity, tissue regeneration, and anti-inflammatory effects in vivo, suggesting a promising approach for treating infected skin wounds.

This study applied a machine learning-based genomic analysis to identify genetic markers associated with wool traits in Central Anatolian Merino sheep, successfully highlighting loci relevant to fiber diameter, staple length, and greasy fleece yield, which could inform breeding programs to enhance wool quality and yield.

This study found that topical rebamipide, originally a gastric ulcer medication, can activate hair follicle stem cells and promote hair regeneration by modulating dermal adipocyte metabolism, with potential targeting of the prostaglandin E receptor EP4.