Skin-Inspired Phototherapeutic Cryogel Ameliorates Infected Wound Healing by Orchestrating Mechanotransduction and Immunomodulation

    November 2025 in “ Bioactive Materials
    Jeong Man An, Md Moniruzzaman, Rumi Acharya … Yong-Kyu Lee
    Studysummary In this study, researchers developed a DNA/GelMA-based cryogel platform that uses phototherapy to combat MRSA infection and promote scarless wound healing, showing enhanced bactericidal activity, tissue regeneration, and anti-inflammatory effects in vivo, suggesting a promising approach for treating infected skin wounds.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 6

    1. Wnt Signaling Modulates Mechanotransduction in the Epidermis to Drive Hair Follicle Regeneration Science Advances · 2025
    2. A Wearable and Stretchable Dual-Wavelength LED Device for Home Care of Chronic Infected Wounds Nature Communications · 2024
    3. Programmable Artificial Skins Achieve Antiscar Healing with Multiple Appendage Regeneration Advanced Materials · 2024
    4. Glycosaminoglycans’ Ability to Promote Wound Healing: From Native Living Macromolecules to Artificial Biomaterials Advanced science · 2023
    5. Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities Signal Transduction and Targeted Therapy · 2022
    6. Mechanisms and Applications of the Anti-Inflammatory Effects of Photobiomodulation AIMS biophysics · 2017