Innate Type 2 Immunity Controls Hair Follicle Commensalism by Demodex Mites

    August 2022 in “ Immunity ”
    Roberto R. Ricardo-González, Maya E. Kotas, Claire E. O’Leary … Richard M. Locksley
    Studysummary This study found that control of Demodex mite colonization in mice required skin ILC2s and IL-13, highlighting their role in maintaining HF integrity and limiting mite overgrowth.
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    Research cited in this study 4

    1. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Cell · 2019
    2. Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices Cell · 2017
    3. Ubiquity and Diversity of Human-Associated Demodex Mites PLoS ONE · 2014
    4. Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin Nature Immunology · 2012