An Important Role of Podoplanin in Hair Follicle Growth

    July 2019 in “ PLoS ONE ”
    Sunyoung Yoon, Lothar C. Dieterich, Carlotta Tacconi … Michael Detmar
    Studysummary This study found that deleting podoplanin in mouse keratinocytes promoted hair follicle growth during regeneration, suggesting it may regulate hair cycling pathways that could aid in treating hair loss conditions.
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    Research cited in this study 7

    1. Pretreatment of Epidermal Growth Factor Promotes Primary Hair Recovery via the Dystrophic Anagen Pathway After Chemotherapy-Induced Alopecia Experimental Dermatology · 2013
    2. Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine Tissue Engineering Part B-reviews · 2012
    3. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    4. Targeting to the Hair Follicles: Current Status and Potential Journal of dermatological science · 2010
    5. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    6. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    7. Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways Proceedings of the National Academy of Sciences of the United States of America · 2000