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Certain immune cells in the skin can stop hair from growing.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Immune cells are essential for skin regeneration using biomaterial scaffolds.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

Aged individuals heal wounds less effectively due to specific immune cell issues.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Pantethine may boost the immune system's ability to fight sarcoma.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.

Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.