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    Glossary Innate Lymphoid Cells

    innate immune cells that respond quickly to infections and inflammation

    Innate Lymphoid Cells (ILCs) are a group of immune cells that play a crucial role in the body's first line of defense against infections and in maintaining tissue homeostasis. Unlike adaptive immune cells, ILCs do not have antigen-specific receptors but can respond quickly to signals from damaged or infected tissues, helping to orchestrate the immune response and inflammation.

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    1. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Cell · 2019 · 181 citations
    2. 937 Disruption of the innate lymphoid cell network alters the hair cycle during induced anagen 2023
    3. Epidermal Notch1 recruits innate lymphoid cells to orchestrate normal skin repair Durham e-Theses (Durham University) · 2014
    4. How the Innate Lymphoid Cells Improved Our Understanding of the Mechanisms of Allergic Diseases and Influenced the Standpoint? Asthma Allergy Immunology · 2024
    5. 431 Innate lymphoid cells type 1 may be new, non-antigen-specific player in the pathogenesis of alopecia areata Journal of Investigative Dermatology · 2019
    6. Innate lymphoid cells type 1 may be new, non-antigen-specific player in the pathogenesis of alopecia areata 2019
    7. Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling Developmental Cell · 2024 · 5 citations
    8. Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair Nature Communications · 2016 · 86 citations
    9. Understanding Type 3 Innate Lymphoid Cells and Crosstalk with the Microbiota: A Skin Connection International journal of molecular sciences · 2024
    10. Targeting lymphoid-derived IL-17 signaling to delay skin aging Nature Aging · 2023 · 59 citations
    11. Fibroblast heterogeneity and tertiary lymphoid tissues in the kidney Immunological Reviews · 2021 · 9 citations
    12. Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models International Journal of Molecular Sciences · 2022 · 5 citations
    13. Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis Nature Communications · 2026
    14. 332 OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity Journal of Investigative Dermatology · 2022
    15. Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata bioRxiv (Cold Spring Harbor Laboratory) · 2022
    16. Innate type 2 immunity controls hair follicle commensalism by Demodex mites Immunity · 2022 · 24 citations
    17. Type 2 innate immunity regulates hair follicle homeostasis to control <i>Demodex</i> pathosymbionts bioRxiv (Cold Spring Harbor Laboratory) · 2021
    18. Mechanisms regulating skin immunity and inflammation Nature Reviews Immunology · 2014 · 610 citations
    19. The developing immune network in human prenatal skin Immunology · 2020 · 11 citations
    20. Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes Frontiers in Immunology · 2021 · 9 citations
    21. 516 Possible role of ILC1 in the pathogenesis of alopecia areata (AA) 2019 · 3 citations
    22. Local IL-17 orchestrates skin aging bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    23. Immunological control of skin development: from homeostasis to developmental pathologies Frontiers in Immunology · 2025
    24. 331 Mitochondrial stress contributes to atopic dermatitis Journal of Investigative Dermatology · 2022
    25. 328 The transcription factor CEBPB is a novel hub gene and multi-functional disease driver in Psoriatic skin inflammation Journal of Investigative Dermatology · 2022
    26. Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata eLife · 2023 · 18 citations
    27. Author response: Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata 2023
    28. Decision letter: Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata 2022
    29. Analysis of the heterogeneity and complexity of murine extraorbital lacrimal gland via single-cell RNA sequencing bioRxiv (Cold Spring Harbor Laboratory) · 2023
    30. ILC3s as central regulators of mucosal homeostasis and disease pathogenesis (Review) International Journal of Molecular Medicine · 2026