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This study found that Pomiferin may effectively stimulate extracellular matrix protein expression in skin and scalp models, with results comparable to retinol, suggesting potential as a topical treatment ingredient.

This study found that a serum-free DMEM-F12 medium with 45% oxygen best supports in vitro development and differentiation of human fetal skin, closely mimicking the in vivo state.

In this study, HYDRO DELUXE BIO was reported to show promise for scalp mesotherapy by enhancing angiogenesis and reducing inflammation in an in vitro model.

This study found that Na CMC hydrogel loaded with PEG-coated silver nanoparticles demonstrated superior antibacterial and wound-healing efficacy compared to commercial silver sulfadiazine cream in a wound-healing model.

In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.

This study found that olorofim demonstrated potent in vitro and in vivo antifungal activity against dermatophytes, resolving skin lesions in a guinea pig model similar to clotrimazole, suggesting it may be a promising treatment for dermatophytosis.

This study found that a long-term astrocyte culture model can effectively study astrocyte senescence and suggests minoxidil as a potential candidate to regulate brain aging by normalizing dysregulated gene expression in aged astrocytes.

In this study, gold nanoparticles-embedded ceria nanoparticles with enhanced antioxidant activities effectively reduced inflammation and colon injury in a colitis mouse model, suggesting their potential as a nano-therapeutic for inflammatory bowel disease.

This study investigated the effects of cedrol on colorectal cancer and found that it inhibited cell proliferation and induced cell cycle arrest and apoptosis in cell models, while in vivo, it suppressed cancer progression and improved survival at a well-tolerated dose.

In this study, researchers found that steroidal 17β-carboxamides 1-4 significantly inhibited 5α-reductase enzyme activity and reduced prostate weight more effectively than finasteride in a hamster model, without toxic side effects, suggesting potential for treating benign prostatic hyperplasia.

In this study, Korean Red Ginseng showed protective effects against chemotherapy-induced premature hair follicle aging in an in vitro model by modulating specific cellular protein expressions.

This study examines the development and application of cultured models for gallbladder carcinoma and highlights innovations and challenges in constructing effective in vitro growth models for cancer research.

This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.

This study found that oral administration of Terminalia bellirica enhanced hair growth in testosterone-suppressed conditions in both human cell and mouse models, outperforming finasteride, a current commercial hair loss treatment.

This study found that high doses of progesterone significantly inhibited neuroblastoma growth in both in vitro and mouse models, while showing selective toxicity and minimal harm to healthy cells.

This study found that the antimicrobial peptide DPK-060 effectively reduced bacterial counts of Staphylococcus aureus and was safe for topical use in preclinical models, although nanocarrier encapsulation did not enhance its efficacy.

This study clarified and quantified the concept of hair transparency using a validated mathematical model based on measurable hair properties and consumer perception data from stylists in Japan and China.

This study found that ascorbigen increased growth of dermal papilla cells but did not significantly protect against chemotherapy-induced alopecia in a mouse model, suggesting limited effectiveness for hair regrowth in this context.

This study found that Orthosiphon stamineus extract significantly stimulated dermal papilla cell proliferation and enhanced hair growth in an ex vivo model of androgenic alopecia compared to vehicle-treated controls.

This study identified several gonadal hormone drugs, including toremifene citrate, tamoxifen citrate, and clomiphene citrate, that effectively inhibited filovirus entry in a pseudovirus model.

This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.

This study found that oxyresveratrol enhanced cell proliferation, reduced oxidative stress and inflammation in vitro, and promoted hair growth in an androgenetic alopecia mouse model, suggesting its potential as a treatment for hair loss.

This study found that MCS nanoparticles improved Minoxidil's hair growth effects in an animal model compared to the commercial formulation, but they were less effective than CS nanoparticles despite showing better solubility with minimal side effects.

This study found that Heated radish extract potently suppressed melanin production in vitro and reduced wrinkle formation and collagen degradation in vivo, suggesting its potential as a skin whitening and antiaging product.

This study found that finasteride and luteolin may prevent hair loss and promote hair growth in vitro and in vivo by modulating specific gene expressions related to cell differentiation and apoptosis.

This study found that Gynostemma pentaphyllum hydrodistillate and Damulin B exert significant anti-photoaging effects in UVB-irradiated models by reducing oxidative stress, improving ECM integrity, and enhancing skin hydration and elasticity.

This study found that N,N-dimethylglycine sodium salt promoted proliferation and migration of cultured human epidermal keratinocytes and had anti-inflammatory and antioxidant effects in vitro.

This study found that coffee extraction and its active compound, caffeotannic acid, showed high enzyme inhibition activity against 5a-reductase in an in vitro model.

This study found that Oriental melon leaf extracts promoted hair growth in a mouse model and cultured human hair follicles, suggesting potential use as a treatment for hair loss.

In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.