Ascorbigen Induces Dermal Papilla Cell Proliferation In Vitro, But Fails To Modulate Chemotherapy-Induced Alopecia In Vivo
March 2013
in “
Phytotherapy Research
”
TLDR Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
The study from 2013 explored the potential of ascorbigen (ABG) to promote hair growth and found that while ABG increased the proliferation of human dermal papilla cells by 1.2-fold in vitro, it did not have the same effect on keratinocytes and failed to prevent or reverse chemotherapy-induced alopecia in a mouse model. The results indicated that ABG is not effective in treating hair loss caused by chemotherapy, and its therapeutic potential for hair growth requires further research. The number of subjects used in the study was not provided.
