The In Vivo and In Vitro Effects of Terminalia Bellirica Fruit Extract on Testosterone-Induced Hair Loss

    Min Jeong Woo, Ha Yeong Kang, So Jeong Paik … Sung Keun Jung
    Studysummary This study found that oral administration of Terminalia bellirica enhanced hair growth in testosterone-suppressed conditions in both human cell and mouse models, outperforming finasteride, a current commercial hair loss treatment.
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    Research cited in this study 23

    1. Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss Journal of Clinical Medicine · 2023
    2. The Molecular Mechanism of Natural Products Activating Wnt/Beta-Catenin Signaling Pathway for Improving Hair Loss Life · 2022
    3. Epidemiological Trends in Alopecia Areata at the Global, Regional, and National Levels Frontiers in immunology · 2022
    4. The Psychological Consequences of Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    5. Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways Frontiers in Medicine · 2022
    6. Nutraceuticals for Androgenetic Alopecia PubMed · 2022
    7. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    8. Perspectives on MicroRNAs Targeting DKK1 for Developing Hair Regeneration Therapy Cells · 2021
    9. Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia Biomedicine & Pharmacotherapy · 2021
    10. Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy Journal of the European Academy of Dermatology and Venereology · 2020
    11. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss International Journal of Molecular Sciences · 2020
    12. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    13. An Overview of Herbal Alternatives in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019
    14. Serenoa Repens Extracts Promote Hair Regeneration and Repair of Hair Loss in Mouse Models by Activating TGF-β and Mitochondrial Signaling Pathway PubMed · 2018
    15. Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-Analysis Acta dermato-venereologica · 2018
    16. Hair Loss: Common Causes and Treatment PubMed · 2017
    17. Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia Molecular and Cellular Endocrinology · 2016
    18. Erbium: YAG Laser (2,940 nm) Treatment Stimulates Hair Growth Through Upregulating Wnt 10b and β-Catenin Expression in C57BL/6 Mice PubMed · 2015
    19. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    20. Overexpression Of Sonic Hedgehog Suppresses Embryonic Hair Follicle Morphogenesis Developmental Biology · 2003
    21. Human Hair: A Unique Physicochemical Composite Journal of the American Academy of Dermatology · 2003
    22. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    23. The Secret Life of the Hair Follicle Trends in genetics · 1992

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