Processed Radish Extract Melanogenesis in Humans and Induces Anti-Photoaging Effects in Ultraviolet B-Induced Hairless Mouse Model
December 2019
New to collagen? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that Heated radish extract potently suppressed melanin production in vitro and reduced wrinkle formation and collagen degradation in vivo, suggesting its potential as a skin whitening and antiaging product.
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The study demonstrated that Heated Radish Extract (HRE) effectively suppressed tyrosinase activity and melanin production in B16/F10 melanoma cells and reduced the expression of melanin production pathway components. In UVB-exposed hairless mice, HRE inhibited MMP expression, reduced wrinkle formation, and prevented collagen degradation. Additionally, a 3% HRE cream improved skin resilience, moisture, and tone in human skin. These findings suggested that HRE could be a potent skin whitening and anti-aging product.
