Processed Radish Extract Melanogenesis in Humans and Induces Anti-Photoaging Effects in Ultraviolet B-Induced Hairless Mouse Model

December 2019

Hyun‐Kyoung Kim

Heated Radish Extract HRE tyrosinase melanin B16/F10 melanoma cells UVB MMP collagen skin resilience skin moisture skin tone radish extract melanin production UVB exposure collagen degradation skin whitening anti-aging

TLDR Heated radish extract may help lighten skin and reduce aging signs.

The study demonstrated that Heated Radish Extract (HRE) effectively suppressed tyrosinase activity and melanin production in B16/F10 melanoma cells and reduced the expression of melanin production pathway components. In UVB-exposed hairless mice, HRE inhibited MMP expression, reduced wrinkle formation, and prevented collagen degradation. Additionally, a 3% HRE cream improved skin resilience, moisture, and tone in human skin. These findings suggested that HRE could be a potent skin whitening and anti-aging product.

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