Pigmentation Effect of Rice Bran Extract in Hair Follicle-Like Tissue and Organ Culture Models

October 2019 in “ Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine ”

Yumi Kim, Han-Moi Lim, Eun-Cheol Lee, Young-Kwon Seo

rice bran extract melanin production hair follicle-like tissue model hair follicle organ culture model melanogenesis-related proteins microphthalmia-associated transcription factor melanin biosynthesis hair follicle melanogenesis RBE melanin HFLT model HF model MITF

TLDR Rice bran extract boosts melanin production in hair follicles.

The study investigated the effect of rice bran extract (RBE) on melanin production using a three-dimensional hair follicle-like tissue (HFLT) model and a hair follicle (HF) organ culture model. RBE treatment significantly increased the expression of melanogenesis-related proteins, including the microphthalmia-associated transcription factor, in both models. The results indicated that RBE promotes melanin biosynthesis, suggesting that the HFLT model could be a valuable tool for studying hair follicle melanogenesis and evaluating new materials for enhancing melanin production.

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