63 citations
,
December 2013 in “PLoS ONE” This study suggests that finasteride may reduce the aggressiveness and invasion of prostate tumors, with effects potentially differing based on the androgen responsiveness of the patient's prostate cells.
51 citations
,
March 2019 in “Experimental Dermatology” This study suggests that in hidradenitis suppurativa, MMP-induced matrix alterations may contribute to inflammation by releasing active peptides and inflammatory factors in the extracellular matrix.
42 citations
,
February 2000 in “Journal of Investigative Dermatology” This study found that Gelatinase A activity is linked to the absence of type VII collagen during human fetal skin development, indicating its role in remodeling the basement membrane zone.
27 citations
,
June 2001 in “International Journal of Dermatology” This study found that cytokine and EGF stimulation leads to increased MMP-9 production in hair follicles, a process involved in hair follicle involution associated with alopecia.
8 citations
,
May 2024 in “Regenerative Therapy” This study found that bioactive glass 1393 accelerates wound healing by promoting angiogenesis through the ROS/P53/MMP9 signaling pathway, enhancing granulation tissue formation and collagen deposition, as evidenced by both in vivo and in vitro experiments.