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In this study of patients with Androgenic Alopecia, micro-grafts containing HD-AFSCs resulted in significantly improved hair density and follicle count over 11 months compared to a saline solution, suggesting a potential alternative therapy for hair regrowth.

In this study, adipose-derived stem cells from superficial adipose tissue showed higher regenerative potential, and more macrophages were found in superficial than deep adipose tissue, potentially influenced by skin microbiota.

This study found that human adipose tissue-derived mesenchymal stem cells inhibited A549 tumor growth but significantly promoted HT-29 tumor growth in mouse models, highlighting opposing effects depending on the cancer type.

In this study, researchers found that human adipose tissue-derived mesenchymal stromal cells exhibit significant phagocytic ability against various particles and pathogens, which might enhance strategies for addressing specific local and systemic infections due to their regenerative properties.

This study found that small extracellular vesicles derived from human adipose tissue could promote soft tissue regeneration and increase M2 macrophage polarization, suggesting a promising cell-free approach to tissue repair.

This study demonstrated that intraoperative bioprinting using a bioink with human adipose-derived extracellular matrix and stem cells achieved successful reconstruction of full-thickness craniomaxillofacial skin defects in rats, promoting wound closure, adipogenesis, and hair follicle-like structure formation within two weeks.

In this study, researchers used single-cell RNA sequencing to identify cell types and molecular differences in subcutaneous adipose tissue from various anatomical sites, suggesting that certain subpopulations of human adipose stem cells might improve the treatment of chronic refractory wounds.

This review discusses the growth factors produced by adipose tissue-derived stem cells that are associated with hair growth stimulation and reports no new clinical findings.

This study demonstrates that dermal white adipose tissue regulates human hair growth and pigmentation through hepatocyte growth factor secretion, highlighting potential therapeutic targets for hair-related disorders.

This study found that melanocyte progenitor cells are present in human subcutaneous adipose tissue and may differentiate into mature melanocytes, suggesting potential applications in treating skin diseases and rejuvenation.

This study found that mesenchymal stem cells derived from dental pulp and adipose tissue have distinct gene expression signatures that suggest potential target diseases for clinical applications.

This study found that human dWAT regulates hair growth and pigmentation through HGF secretion, highlighting potential novel targets for treating hair growth and pigmentation disorders.

In this study, researchers found that eccrine sweat glands in human scalp skin are morphologically integrated into the pilosebaceous unit, suggesting they form a common homeostatic tissue environment with adjacent structures.

This study found that combining mesenchymal stromal cells from adipose tissue and hair follicles with soy protein and β-chitin scaffolds significantly reduced wound healing time and improved skin regeneration in vivo.

This study found that dermal white adipose tissue surrounding human hair follicles enhances proliferation, pigmentation, and hair shaft elongation in an ex vivo setting.

This review discusses the paracrine effects of adipose tissue-derived stem cells on surrounding cells and tissues, noting their potential therapeutic benefits, but reports no new clinical results.

This study demonstrated that adding human adipose-derived stem cells to hair follicle germ-like aggregates significantly improved hair shaft generation in transplanted nude mice, suggesting a promising strategy for hair regenerative medicine.

This study suggests that specific mutations in the MFN2 gene, including the p.Arg707Trp allele, can result in tissue-selective mitochondrial dysfunction leading to excessive upper body fat growth and low leptin levels.

This study found that telocytes in human scalp tissue were located around hair follicles and glands and may be involved in skin regeneration and homeostasis.

This study concluded that platelet concentrates can promote both soft and hard tissue regeneration, suggesting their potential application in clinical regenerative therapies.

This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.

This review discusses the use of human mesenchymal stem cells (hMSCs) for treating skin diseases and suggests they show promise for improving conditions like wounds and scleroderma, but more research is needed due to varied study designs and endpoints.

This review suggests that stem cells might be a promising addition or alternative to standard treatments for androgenic alopecia, but larger studies are needed to confirm these findings.

In this study, hair follicle-derived mesenchymal stromal cells showed potential for immunomodulation, with equivalent or superior responses compared to those from adipose tissue, suggesting a promising alternative cell source.

Human hair keratin can help repair fat tissue.

This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.

This practical guide introduces methods to study human dermal white adipose tissue but does not report new clinical results, emphasizing available techniques and staining protocols.

In this study, aleglitazar and its metabolite M6 were evaluated for safety in non-clinical settings, revealing organ-targeting effects common to PPAR agonists but no significant tumor increase in rat carcinogenicity studies, supporting progression to Phase 3 clinical trials.

In this study, an immortalized MSC line from human adipose tissue showed potential for applications in regenerative medicine and inflammatory diseases through production of active factors, demonstrated in vitro.