Therapeutic Effect of a Xeno-Free Three-Dimensional Stem Cell Mass in a Hind Limb Ischemia Model

September 2018 in “ Tissue Engineering Part A ”

Thanavel Rajangam, Kyoung-Sik Moon, Do Kyun Kim … Sang-Heon Kim

xeno-free three-dimensional stem cell masses XF-3DCMs human adipose stem cells hASCs fetal bovine serum-derived 3DCMs FBS-3DCMs pro-angiogenic factor angiogenesis markers neovascularization tissue regeneration tumorigenicity immunogenicity critical limb ischemia peripheral artery disease stem cell therapy adipose stem cells fetal bovine serum angiogenesis blood vessel growth tissue repair tumor formation immune response limb ischemia artery disease

Studysummary This study found that injecting xeno-free, three-dimensional cell masses from human adipose-derived stem cells improved blood perfusion and preserved limb function in mice without causing tumors or toxicity, suggesting potential for treating severe ischemic diseases.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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