TLDR Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
In the 2018 study, researchers found that conditioned media from deer antlerogenic mesenchymal stem cells (DaMSC-CM) could promote tissue regeneration, including hair regeneration, more effectively than media from adipose tissue-derived stem cells. The DaMSC-CM contained novel round vesicles, approximately 120 nm in diameter, which could regulate gene expression related to tissue renewal, such as Wnt-3a, Wnt-10b, and LEF-1. These findings suggest that DaMSC-CM and its secretory vesicles could have therapeutic applications for tissue regeneration. The study focused on cellular and molecular mechanisms and did not involve human subjects.
45 citations
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April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
66 citations
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July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
83 citations
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January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
60 citations
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January 2015 in “World Journal of Stem Cells” Stem cells and biomaterials are key to improving skin substitutes for medical use.
35 citations
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January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
232 citations
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June 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling helps heal injuries and could lead to new treatments.
24 citations
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February 2006 in “Chinese Medical Journal” Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
April 2019 in “Journal of Investigative Dermatology” Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.
17 citations
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December 2010 in “Journal of Investigative Dermatology” Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
