research Aqueous Extract of Asiasari Radix Inhibits Formalin-Induced Hyperalgesia via NMDA Receptors
Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
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research Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production
A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
research Fluridil, A Rationally Designed Topical Agent For Androgenetic Alopecia: First Clinical Experience
Fluridil safely promotes hair growth in men with androgenetic alopecia.
research Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
research Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research Enhanced Skin Permeation of 5α-Reductase Inhibitors Entrapped into Surface-Modified Liquid Crystalline Nanoparticles
Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.
research Stereocontrolled Synthesis of All Eight Stereoisomers of the Putative Anti-Androgen Cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research The Penetration Enhancer SEPA Augments Stimulation of Scalp Hair Growth by Topical Minoxidil in the Balding Stumptail Macaque
SEPA™ enhances the effectiveness of minoxidil in stimulating hair growth, working faster and better than Rogaine® TS, with no significant side effects.
research Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
research Exploring the Potential of Minoxidil Tretinoin Liposomal-Based Hydrogel for Topical Delivery in the Treatment of Androgenic Alopecia
Minoxidil tretinoin liposomal based hydrogel shows promise for effective treatment of hair loss by delivering both drugs at the same time.
research Development of Optimized Self-Nanoemulsifying Lyophilized Tablets to Improve Finasteride Clinical Pharmacokinetic Behavior
Improved tablets lead to faster, better drug absorption for hair loss treatment.
research A New Label-Free Screen for Steroid 5α-Reductase Inhibitors Using LC-MS
Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
research Iontophoretic Transdermal Delivery of Finasteride in Vesicular Invasomal Carriers
Finasteride delivery through skin improved using invasomes and iontophoresis.
research Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways
Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.
research Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2
Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.
research Development of a New GC-MS/MS Method for the Determination of Metformin in Human Hair
A new method was created to measure metformin in hair, showing potential for monitoring treatment and medical investigations.
research Development of Finasteride/PHBV@Polyvinyl Alcohol/Chitosan Reservoir-Type Microspheres as a Potential Embolic Agent: From In Vitro Evaluation to Animal Study
Created microspheres show potential for safe and effective use in prostate artery embolization.
research Lanostane-Type Triterpenes from the Sclerotium of Inonotus Obliquus (Chaga Mushrooms) as Proproliferative Agents on Human Follicle Dermal Papilla Cells
Chaga mushrooms contain compounds that may promote hair growth better than common treatments.
research Preformulation Studies of Finasteride to Design Matrix Systems for Topical Delivery
research Steroid 5α-Reductase 2 Deficiency Leads to Reduced Dominance-Related and Impulse-Control Behaviors
Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
research Topical Formulations Containing Finasteride: Determination of Finasteride Penetration into Hair Follicles Using the Differential Stripping Technique
Formulation P-08-016 better targets hair follicles for baldness treatment.
research In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
Ketoconazole increases finasteride's effectiveness and lifespan in the body.
research Analytical Chemistry Studying Historical Pharmaceuticals and Health Care Formulations
Analytical chemistry helps understand the makeup and use of ancient medicines, but it's complex and challenging.
research Co-Loading of Finasteride and Baicalin in Phospholipid Vesicles Tailored for the Treatment of Hair Disorders
Finasteride and baicalin in phospholipid vesicles effectively promote hair growth and increase follicle count.
research Niosomal Delivery of Pumpkin Seed Oil: Development, Characterization, and Physical Stability
The pumpkin seed oil niosomes are promising for skin and hair treatments because they are stable and effectively deliver the oil.
research Minoxidil-Encapsulated Poly(L-Lactide-Co-Glycolide) Nanoparticles with Hair Follicle Delivery Properties Prepared Using Solvent Evaporation and Sonication
Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.
research An Asian Traditional Herbal Complex Containing Houttuynia Cordata Thunb, Perilla Frutescens Var. Acuta, and Green Tea Stimulates Hair Growth in Mice
The Asian herbal mix with Houttuynia cordata, Perilla frutescens, and green tea helped grow hair in mice.
research Hair Growth Promoting and Anticancer Effects of p21-Activated Kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia Zerumbet
Compounds from Alpinia zerumbet may help with hair regrowth and cancer treatment by targeting PAK1.
research In Vitro Selective Inhibition of Human UDP-Glucuronosyltransferase (UGT) 1A4 by Finasteride and Prediction of In Vivo Drug–Drug Interactions
Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.