Co-Loading of Finasteride and Baicalin in Phospholipid Vesicles Tailored for the Treatment of Hair Disorders

August 2020 in “ Nanoscale ”

Silvia Mir-Palomo, Amparo Nácher, M A Ofelia Vila-Busó, Carla Caddeo, Maria Letizia Manca, Amparo Ruiz Saurí, Elvira Escribano-Ferrer, Maria Manconi, Octavio Díez-Sales

finasteride baicalin phospholipid vesicles glycerol-hyalurosomes hair growth hair follicles local treatment of hair loss Propecia

TLDR Finasteride and baicalin in phospholipid vesicles effectively promote hair growth and increase follicle count.

The study explores the use of phospholipid vesicles co-loaded with finasteride and baicalin for the treatment of hair disorders. The co-loading of these drugs in glycerol-hyalurosomes was found to be the most effective formulation in promoting hair growth and increasing the number of follicles in treated mice. The study suggests that this approach could represent a promising tool for the local treatment of hair loss.

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17 / 17 results

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2 / 2 results

research A Case of Hidradenitis Suppurativa Treated Effectively by Finasteride

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Finasteride effectively treated hidradenitis suppurativa.

research Erythema Annulare Centrifugum Secondary to Treatment with Finasteride

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Co-Loading of Finasteride and Baicalin in Phospholipid Vesicles Tailored for the Treatment of Hair Disorders

Cited in this study

research Finasteride Enhances Stem Cell Signals of Human Dermal Papilla Cells

research Complementary and Alternative Treatments for Alopecia: A Comprehensive Review

research New Drugs Under Investigation for the Treatment of Alopecias

research Finasteride Topical Delivery Systems for Androgenetic Alopecia

research Hair Growth Promoting Activity of Cedrol Isolated from the Leaves of Platycladus Orientalis

research Penetration Profile and Human Cadaver Skin Distribution of Finasteride from Vesicular Nanocarriers

research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

research Baicalin, A Flavonoid, Affects The Activity Of Human Dermal Papilla Cells And Promotes Anagen Induction In Mice

research Delivery and Targeting of Nanoparticles into Hair Follicles

research Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth

research The Inhibitory Effect of Scutellaria Baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia

research Finasteride 5 mg/Day Treatment of Patterned Hair Loss in Normo-Androgenetic Postmenopausal Women

research Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling

research In Vitro Percutaneous Permeation and Skin Accumulation of Finasteride Using Vesicular Ethosomal Carriers

research Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes

research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia

research Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia

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