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    Finasteride Enhances Stem Cell Signals of Human Dermal Papilla Cells

    January 2019 in “ in Vivo ”
    Napapat Rattanachitthawat, Tatchakorn Pinkhien, Praneet Opanasopit … Pithi Chanvorachote
    Studysummary In this study, finasteride was found to enhance stem cell properties in dermal papilla cells, suggesting potential benefits for hair loss management and regenerative therapies.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. An Investigation of Crosstalk Between Wnt/β-Catenin and Transforming Growth Factor-β Signaling in Androgenetic Alopecia Medicine · 2016
    2. Glycyrrhizic Acid Attenuates Stem Cell-Like Phenotypes of Human Dermal Papilla Cells Phytomedicine · 2015
    3. Persistent Sexual Dysfunction and Depression in Finasteride Users for Male Pattern Hair Loss: A Serious Concern or Red Herring? PubMed · 2014
    4. New Investigational Drugs for Androgenetic Alopecia Expert Opinion on Investigational Drugs · 2013
    5. The Role of Androgen and Androgen Receptor in Skin-Related Disorders Archives of Dermatological Research · 2012
    6. Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia British Journal of Dermatology · 2012
    7. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011
    8. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    9. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    10. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    11. Finasteride: Its Impact on Sexual Function and Prostate Cancer Journal of Cutaneous and Aesthetic Surgery · 2009
    12. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    13. α3β1-Integrin Regulates Hair Follicle But Not Interfollicular Morphogenesis in Adult Epidermis Journal of Cell Science · 2003
    14. Changing Patterns of Localization of Putative Stem Cells in Developing Human Hair Follicles Journal of Investigative Dermatology · 2000